62 results about "Emotional disorder" patented technology

An emotion monitoring method for special people includes: acquiring neural physiological information, and acquiring electroencephalogram signal and brain blood oxygen signal; performing signal treatments including signal pretreatment, feature extraction and emotion recognition; determining intervention type, determining recognized emotions, and returning to a start phase to continue monitoring if a user is calm or positive emotionally, or proceeding a next phase if not; performing systematic intervention, namely determining the manner of systematic auxiliary emotion regulation and intervention or remote intervention according to different emotions; and storing data, drawing an emotion periodic table in a certain period, and recording and storing mood fluctuations of a user. By the aid of portable detection of electroencephalogram and brain blood oxygen signals, accurate emotion status is recognized, unhealthy emotions of users and the outside world can be helped and noticed timely, humane placation measures are taken, emotion statuses of the users can be improved, mental state deterioration can be avoided for the users, and nursing burden and physiological pressure of family members of a patient with emotional disorder can also be relieved.

A system and method for diagnosing mental or emotional disorders is disclosed. An affective BCI component is incorporated into a closed loop, symptom—responsive psychiatric DBS system. A series of input data related to a brain of the patient is acquired while the patient performs a battery of behavioral tasks. From the patient's performance on the task battery, the system identifies what is abnormal for that individual patient in terms of functional domains. Patient-specific behavioral measurements are then linked to patterns of activation and de-activation across different brain regions, identifying specific structures that are the source of the patient's individual impairment.

The present invention concerns the methods and compositions for treating depression and other behavioral and / or emotional disorders of the central nervous system by administering an agonist of hedgehog signaling. Other disorders amenable to treatment by the subject method include attention deficit hyperactive disorders, non-Alzheimer dementia, and various symptoms of memory loss. The present invention also concerns the methods and compositions for enhancing memory and / or cognitive functions, both in a patient suffering from ailment affecting these functions, and in a subject with no diagnosed deficit in memory or cognitive function. The methods and compositions of the present invention stimulate neurogenesis and differentiation, and enhance synaptic transmission of neurons.

The invention discloses a method for screening, evaluating and intervening senile syndromes of hospitalized senile patients, which comprises the following steps of: comprehensively screening the senile syndromes of the senile patients; carrying out special assessments including pressure sore risk degree, disability degree, emotional disorder degree, sleep quality, cognitive disorder degree, malnutrition degree, dysphagia degree, defecation and urination, social support, pain, delirium, tumble, sarcopenia, weakness, body diseases and the like; and making individualized intervention suggestions according to the evaluation conclusion. According to the invention, elderly health management is associated with different states of diseases, an elderly syndrome intelligent management method is provided for elderly patients in a targeted manner, and disease hierarchical management and continuous service are realized. The method comprises a complete process of health information collection, disease and function evaluation, intervention opinions and follow-up visits, so that the method can be widely popularized as a special diagnosis and treatment technical method of the elderly medical inpatient department, and can enable the elderly to obtain better standard, effective and homogenized services.

The invention relates to methods and products for treating emotional disorders such as stress induced emotional disorders, as well as related assays and kits. Methods include administering to a subject an effective amount of an agent for targeting the Rac1, Cdk5, p35, PAK-1 pathway to treat the emotional disorder. The agent for targeting the Rac1, Cdk5, p35, PAK-1 pathway may be, for instance a Rac-1 inhibitor, a Cdk5 inhibitor, a PAK-1 activator, or p35 mobilizing agent.

The invention provides traditional Chinese medicine composition for treating depression insomnia. The traditional Chinese medicine composition is prepared from 30-60 parts by weight of spina date seed extract and 30-60 parts by weight of albizia flower extract, wherein the content of saponin in the spina date seed extract is larger than or equal to 85.0%, and saponin has effects of heart nourishing, mind tranquilizing, sedation, hypnosis, arrhythmia resistance and myocardial ischemia resistance, has certain pressure reduction effect and is one of main components with sedative and hypnotic effects, thereby having quite good effect of improving sleep; the total flavonoid content of the albizia flower extract is larger than or equal to 35%, and flavonoid compounds have effects of depression resistance, anxiety resistance, scavenging of hydroxyl radicals and the like and has significant pharmacological activity in aspects of treatment of depression, schizophrenia, cancer and the like. Therefore, spina date seeds and albizia flowers in the formula form a medicine pair, the composition is simple, convenient, effective and economic, has functions of soothing the liver, relieving depression, tranquilizing mind, regulating qi and harmonizing the stomach, and is used for treating emotional disorder, depression insomnia, chest distress, anorexia and the like.

The invention discloses a Chinese herba preparation for treating chronic ulcerative colitis. In the traditional Chinese medicine, the chronic ulcerative colitis is categorized as dysentery, diarrhea and intestinal afflux, and caused by dysfunction of the spleen in transport, internal hot and humid condition, large intestine hot-damp accumulation, intestial injury and sepsis syndrome due to eating disorder and emotional disorder and overwork. In order to solve the problems, the Chinese herba preparation is decocted into decoction in preparation department by adopting the following traditional Chinese materials: white flower cacalia seed, sedum sarmentosum, abutilon fiber, manyleaf meadowure rhizome and root, salvia chinensis, mock-strawberry, verbena, tropaeolum, potentilla cryptotaeniae, humifuse euphorbia herb, campsis grandiflora, panax japonicas, folium callicarpae pedunculatae, white atractylodes rhizome, rhizoma polygonati, arillus longan and liquorice. According to the clinical test, the total effective rate is 95.6%, and the recovery rate and colonoscopy results before and after the treatment are remarkably better than those of the control group.

The invention provides a pharmaceutical composition comprising a 5-HT1A receptor stimulant and a mood stabilizer. In the pharmaceutical composition, the weight ratio of the 5-HT1A receptor stimulant to the mood stabilizer is (1-40):(50-800). The invention also provides application of the pharmaceutical composition. Through combination of selective 5-HT1A receptor stimulant and the mood stabilizer which have different action mechanisms, the drug can treat anxiety, depression and / or biphasic emotional disorder and the like at the same time; the disease treatment spectrum is wider; furthermore, the curative effect after combination is more significant than that of single medicine, and the toxic and side effects are lower; a novel drug selection is provided to patients who are intolerant to first-line anti-anxiety or anti-depression or drugs.

The invention discloses a digital auditory integrated training system, which comprises a signal source, a power supply, a host and a signal receiving device, the host is electrically connected with the power supply, the signal source is connected with the host by a signal line, and the signal receiving device is communicated and connected with the host. The digital auditory integrated training system of the invention can correct the disorder phenomena of the auditory system on the voice treatment and stimulate the cerebral cortex by listening to a group of music after filtration and modulation, thus achieving the purpose of improving behavior disorders and emotional disorders. The digital auditory integrated training system is safe and reliable, the treatment has no side effects which are serious and existed for a long time, and the digital auditory integrated training system is applicable to: pervasive developmental disorder (PDD), including autism (Infantile Autism) and Asperger syndrome; attention deficit hyperactivity disorder (ADHD); special speech and language developmental disorder (SLD); emotion disorder (ED); learning disorder (LD) and so on.

The present invention provides a group of tobacco alkaloids, tobacco extract, Yerbamaté extract, and an extract of chewing gum and lozenges which are modulators of monoamine oxidase (MAO) activity (i.e., compounds and substances which inhibit MAO enzyme and prevent its biological activity). The MAO inhibitors of the present invention can cause an increase in the level of norepinephrine, dopamine, and serotonin in the brain and other tissues, and thus can cause a wide variety of pharmacological effects mediated by their effects on these compounds. The MAO inhibitors of the present invention are useful for a variety of therapeutic applications, such as the treatment of depression, disorders of attention and focus, mood and emotional disorders, Parkinson's disease, extrapyramidal disorders, hypertension, substance abuse, smoking substitution, anti-depression therapy, eating disorders, withdrawal syndromes, and the cessation of smoking.

The invention belongs to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for treating depression and emotional disorder diseases. The composition is prepared from the following components in parts by weight: 12-20 parts of Chinese thorowax roots, 12-20 parts of Chinese angelica, 12-20 parts of poria cocos, 12-20 parts of debark peony roots, 12-20 parts of largehead atractylodes rhizomes, 3-8 parts of raw ginger, 3-8 parts of mint, 3-8 parts of prepared liquorice and 2-6 parts of donkey-hide gelatin. The invention alsodiscloses a preparation method of the traditional Chinese medicine composition. The Chinese angelica, the debark peony roots and the Chinese thorowax roots have the effects of stabilizing the mood ofa patient and relieving depression, and have the characteristics of less side effects and no dependence compared with western medicines. The traditional Chinese medicine components have synergistic effect, and the composition is mild in medicinal property, gives consideration to deficiency and excess, has high safety, and improves the curative effect of depression and the compliance of patients.

The invention provides a method for inhibiting melatonin secretion by using a light source. According to the method, a lighting device is specially designed to emit lighting light having a specific wavelength within the wavelength range of 581nm and 590nm, and various experimental data have proved that the lighting light can be used to serve as a melatonin secretion inhibitor. Therefore, the experimental data have proved that the lighting device of the invention is suitable for being used for light therapy for winter depression, thereby treating the seasonal affective disorder (namely the winter depression) by inhibiting the melatonin secretion. Briefly speaking, after a patient suffering from the winter depression receives a treatment course of the light therapy with the lighting light with the wavelength range of 581-590nm, the symptoms of the winter depression, including somnolence, emotional disorder and the like, of the patient suffering from the winter depression can be cured finally due to the fact that the patient has a good mental state and a stable emotional state.

The invention discloses a traditional Chinese medicine composition for treating schizophrenia. Schizophrenia belongs to the category of depressive psychosis and manic psychosis in the traditional Chinese medicine, the disease location is in the mysterious mechanism and is associated with liver, gallbladder, heart and spleen, and leads to unsmooth visceral-qi, yin-yang disharmony and disordered mysterious mechanism to cause emotional disorder due to factors such as stagnation of qi, phlegm stasis, blood stasis and the like. The traditional Chinese medicine composition prepared by the invention is prepared from the following traditional Chinese medicines which tonifies qi, activates blood, reduces stasis and cleans away heat and is prepared as a decoction by water: rhizome of longspurred fairybells, Japanese angelica tree root barks, campsis grandiflora, daphne odera, litmus, cymbidium pendulum, Yunnan alstonia roots and water hyacinth. Through clinical tests, the total effective rate is 93.33% which is remarkably superior to that of a control group and is of comparability (P is greater than 0.05).

The invention discloses a capsule for treating emotional diseases which comprises the constituents of (by weight ratio) pilose asiabell root 25-35 parts, finger citron 13-23 parts, cinnamon twig 7-17 parts, monkshood 2-12 parts, lepidium seed 7-17 parts, green tangerine orange peel 3-13 part, Sparganiaceae 4-14 parts, zedoary 4-14 parts, curcuma root 7-17 parts, bupleurum root 11-21 parts, poria cocos wolf 25-35 parts, ophiopogon root 15-25 parts, prepared dark Japanese plum 25-35 parts, prepared licorice root 3-13 parts, malt 13-23 parts, haw 7-17 parts.

The invention discloses application of a rat model with depression related to a chronic pain in researching on an action mechanism and targets of an antidepressant on pain. According to the model, lumbar 5 spinal nerve of a rat is ligated to cause distinct mechanical hyperalgesia and abnormal pain, accomplished with depression symptom. Then the ligation is released, and the abnormal pain behaviors of animals gradually disappear, but the psychiatric symptoms continue to exist. The depression model prepared by the invention can simulate a clinical phenomenon which is that pains disappear but emotional disorders still exist after treatment for the chronic pain patients, and then the action mechanism and the targets of the antidepressant on pain is understood from the source.

The present invention provides compounds represented by general formula (I), wherein the substituents are as defined in the application. The compounds are useful in the treatment of affective disorders including depression, anxiety disorders including generalized anxiety disorder, panic disorder and obsessive-compulsive disorder.

The invention relates to a medicament for treating arrhythmia, in particular to a Chinese medicine composition which is prepared by using plant Chinese herbal medicines as raw materials and is used for treating arrhythmia. The Chinese medicine composition is characterized by comprising the following raw medicines for preparing effective components of the composite by weight: 10-18g of codonopsis pilosula, 5-15g of astragalus mongholicus, 5-15g of angelica sinensis, 5-15g of rehmanniae praeparat, 5-15g of salvia miltiorrhiza bunge, 4-12g of safflower, 4-12g of Chinese yam, 4-12g of poria cocos, 3-8g of platycladi seed, 3-8g of spina date seed, 3-8g of Chinese magnoliavine fruit and 3-8g of radix glycyrrhizae preparata. The matching of the medicines of the invention brings out the best in each other; the Chinese medicine composition has the effects of tonifying spleen and qi, harmonizing the stomach, nourishing the blood, tonifying lung, consolidating superficies, nourishing heart, calming the nerves, supplementing and activating blood, nourishing kidney, promoting the production of body fluid, tonifying qi, restoring pulse, and the like; through the synergy of the medicament effects, the Chinese medicine composition provided by the invention can treat both principal and secondary aspects of diseases and has no side effect; and the invention has obvious curative effect mainly on arrhythmia caused by yin and yang asthenic disease of qi blood of internal organs, internal injury due to emotional disorder, heart malnutrition due to interaction of qi stagnation and blood stasis and heart vessel unsmoothness.

The invention discloses a wearable system based on physiological data of multiple modes. The system comprises a wearable device and an intelligent terminal, the wearable device measures the physiological data of multiple modes of a user in a non-invasive mode and comprises an intelligent electroencephalogram cap, intelligent earphones and intelligent bracelets, and the intelligent electroencephalogram cap is used for collecting electroencephalogram signals; the intelligent earphones are used for collecting heartbeat sound signals in ear canals through a microphone; and the intelligent bracelets are used for collecting pulse signals. The intelligent terminal is set to filter and normalize the received electroencephalogram signals, heartbeat sound signals and pulse signals, extract features from corresponding time-frequency diagrams respectively, obtain fused feature vectors through feature weighting, and further input the fused feature vectors into a pre-trained deep learning model to obtain a detection result of the emotional disorder. The wearable system has the advantages of noninvasive property, convenience, comfort, low cost, real-time monitoring and the like, and is high in recognition accuracy.

The invention discloses a traditional Chinese herbal medicine for treating hypertension and a making method and application of the traditional Chinese herbal medicine. The traditional Chinese herbal medicine comprises radix bupleuri, schisandra chinensis, cortex albiziae, wild jujube seeds, senecio cineraria, magnetite, polygala tenuifolia, chinese yams, gynostemma pentaphyllum, parasitic loranthus, ramulus uncariae cum uncis, gastrodia elata, prepared rehmannia roots, cortex moutan, tribulus terrestris, rhizoma curculiginis, morinda officinalis, cyperus rotundus, actinolite, curcuma aromatic,grape seeds, ginkgo leaves, cistanche deserticola, human placentas, astragalus membranaceus, angelica sinensis, caulis spatholobi, carthamus tinctorius, cinnamon, nacre mother of pearls, motherwort and achyranthes bidentata. Through traditional Chinese medicine matching, the problems of emotional disorder, mood fickleness and irascibility can be solved, the problem of concentrating and balancingphysique is solved, target treatment on blood purification and fat reduction is achieved, blood vessels are softened, blood vessels are expanded, and the like. Therefore, the purpose of substantiallytreating hypertension can be achieved.

The invention belongs to the field of medical treatment, and specifically relates to a device and a method for evaluating tinnitus treatment effect by using a position location technology. A data acquisition unit is connected with a digital signal processor unit by signals. A digital signal processor is connected with a data evaluation unit by signals. The data evaluation unit is connected with a display unit by signals. The digital signal processor is also communicated with a data storage unit and a data transmission unit by bidirectional signals. A power management unit supplies power for the rest units. The concrete performance of the device and the method is how many times a tinnitus patient goes to leisure activities in a week and how many times the tinnitus patient goes shopping in a week, and other activity range sizes, if the activity ranges of the tinnitus patient have differences before treatment and after treatment, the tinnitus treatment has effect, and the larger the differences are, the better the effect is. Because tinnitus always makes the patient have anxious and other emotional disorder, activity ranges of the tinnitus patients are very small. Therefore, through acquiring position information of the activity ranges of the tinnitus patients, treatment effect of the tinnitus patients can be evaluated, so as to evaluate and record treatment effects of tinnitus scientifically, objectively, and effectively.

The invention discloses an emotion disease symptom extrusion model-building apparatus and method thereof. The extrusion model-building object can be protected by a cage body and is extruded by an automatic control extrusion device, on-site video, audio and endured pressure information and body weight information of the model-building object can be obtained in real time, furthermore, the invention also comprises a protection apparatus for the experiment object. Accordingly, the invention can obtain a plurality of on-site data and provide more basic data for subsequent research work.

The invention relates to a traditional Chinese medicine preparation for treatment of diabetes and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following raw materials: the effective components: lalang grass rhizome, aubergine root, astragalus, lycianthes biflora, root of hollyhock, inula flower, day lily, japanese cayratia herb, cortex fraxini, anoectochilus roxburghii, lettuce, chinese mesona herb, watermeion peel, myrtle, sophora flower and rayal jelly. The traditional Chinese medicine preparation for treatment of diabetes is made of pure traditional Chinese medicine and is made by modern advanced medicine preparation technologies. After being taken, the traditional Chinese medicine preparation for treatment of diabetes has the function of lowering blood glucose; aiming at the reasons such as deficiency of kidney and consumptive thirst, emotional disorder, indigestion in the stomach, dryness due to thermalization and the like causing the diabetes, for realizing the purposes of nourishing, soothing the liver and producing saliva, regulating vital energy and eliminating evil, the traditional Chinese medicine preparation for treatment of diabetes has the functions of eliminating phlegm by cooling, eliminating depression and consumptive thirst, and balancing dryness and moisture, the absorption effect is good, the curative effect is remarkable, and clinical verifications prove that the traditional Chinese medicine preparation for treatment of diabetes is applicable to relieving and treating the diabetes and the diabetic complication.

The invention aims to provide an external application traditional Chinese medicinal preparation for treating the chronic appendicitis. According to the traditional Chinese medicine, the lesion of the chronic appendicitis is in the intestines, and the chronic appendicitis is mainly caused by intestinal transfar division such as improper diet, overfeeding of greasy and raw or cold food, improper cold temperature and emotional disorder and qi movement glomus blockage. Therefore, the traditional Chinese medicines of mirabilitum dehydratum, souliea vaginata, Chinese squill, armillaria tabescens, eye crane, herba ajugae and semen litchi which have the effects of clearing heat, performing detoxifying and dissipating the blood stasis to stop pain are ground and are mixed by honey to be pasty; the traditional Chinese medicinal preparation is externally applied to the most painful part on the stomach; and the clinical test shows that the total efficiency is up to 95 percent.

The invention provides a multi-modal user emotion analysis method based on a knowledge graph. The method comprises the steps of acquiring an emotion analysis service request of a user is received or authorization of social network data of the monitored user applied to emotion analysis service; acquiring user social network data, establishing a user graph model based on the user social network data, the user graph model comprises a data graph DGraph, an information graph IGraph and a knowledge graph KGraph, and storing DDIK, IDIK and KDIK resources respectively; extracting an interactive relationship tuple Inter (user) of the user and other people from the user graph model, substituting the Inter (user) into the function for calculation, and analyzing the emotional tendency of the user according to a calculation result; and sending the emotion tendency analysis result to the corresponding user. According to the method, the emotional tendency of the user can be analyzed based on massivesocial network data under the condition that the user does not perceive, so that the user is helped to know the emotional tendency situation in time, and emotional disorders are prevented.

The invention provides a musical therapy for a CFS emotional disorder. The musical therapy comprises the first step of introducing the scientificity, superiority and necessity of the musical therapy to a patient, the second step of selecting music in a dialectic mode according to the TCM syndrome of the patient, the third step of playing the music, introducing the connotation and the background of the music to the patient and guiding the patient to the artistic conception, wherein each therapy lasts one hour, 55-65 dB, 2 times per day, the music is played for 5 days in every week, 2 days are for resting, and four weeks serve as one course of treatment, and the fourth step of selecting music for treatment in a dialectic mode according to the actual conditions of the patient after the course of treatment is over and circulating the steps. The musical therapy has the advantages that emotional symptoms of somatization, obsessive-compulsive disorder, depression, anxiety, hostility and the like can be effectively relieved, and a certain relaxation effects are achieved on a CFS, the musical therapy belongs to the non-drug treatment means and does not have toxic and side effects of the drug therapy, thereby being high in safety; furthermore, the musical therapy has the treatment characteristics of individuation and syndrome differentiation, the music can be selected according to the different TCM syndromes of patients, operation is easy and convenient, cost is low, and therefore the musical therapy is worth popularizing and applying in communities and families.

The present invention relates to fermented nutritional compositions comprising high concentration of lactosem such as 6 grams per 100 ml, and optionally non-digestible oligosaccharides, such as galactooligosaccharides or fructooligosaccharides for improving the bioavailability of iron and preventing or treating of iron deficiency (anaemia), in particular for infants and young children or pregnant women. In another aspect of the invention, the nutritional composition are used for preventing cognitive disorders and / or socio-emotional disorders in an infant and / or young child.

The invention discloses a Chinese medicine composition for treating chronic ulcerative colitis. The Chinese medicine composition comprises the Chinese medicinal herbs: flabelate maiden-hair herb, root of smalleaf desmodium, silverweed cinquefoil root, emperor woodbetony root, sword bean, syringa pinnatifolia, gorse, hairy waxmyrtle bark, tetracera scandens and chinese granesbill. Through clinical tests in our hospital, the traditional Chinese medicine considers that the chronic ulcerative colitis belongs to categories of 'lingering dysentery, diarrhoea, hematochezia and spouting bleeding from anus', and is caused by externally infection of dampness pathogen, improper diet, emotional disorder and insufficiency of natural endowment. Spleen and kidney deficiencies are symptoms, dampness, cold, fever, qi stagnation, blood stasis and the like are root causes. Through clinical tests in our hospital, the cure rate and the total effective rate of a treatment group are respectively 54.3 percent and 97.8 percent, and remarkably superior to the cure rate and the total effective rate of a control group,namely respectively 23.9 percent and 73.9 percent; the Chinese medicine composition is small in side effects, low in recurrence rate, and worthy of clinical popularization and application.

The invention relates to methods and products for treating emotional disorders such as stress induced emotional disorders, as well as related assays and kits. Methods include administering to a subject an effective amount of an agent for targeting the Rac1, Cdk5, p35, PAK-1 pathway to treat the emotional disorder. The agent for targeting the Rac1, Cdk5, p35, PAK-1 pathway may be, for instance, a Rac-1 inhibitor, a Cdk5 inhibitor, a PAK-1 activator, or p35 mobilizing agent.

The invention discloses an olanzapine-fluoxetine compound capsule preparation and a preparation method thereof, which are used for the drug treatment of bipolar affective disorder. The compound preparation contains two different pellets, which are respectively enteric-coated olanzapine-containing Flat sustained-release pellets and gastric-soluble fluoxetine-containing sustained-release pellets; the olanzapine-fluoxetine compound capsule preparation of the present invention is combined according to the different in vivo pharmacokinetic laws of olanzapine and fluoxetine Two types of pellets with different ratios and different release parts complete the preparation of products of different specifications; achieve rapid onset of effect, synergistic effect, and reduce the number of times of taking medicine.