Compound preparation for preparing dextromethorphan or physiologically acceptable salts thereof and guaifenesin

A technology of guaifenesin and compound preparations, which is applied in the direction of pharmaceutical formulations, ether/acetal active ingredients, medical preparations containing active ingredients, etc. Pain etc.
CN103565810AInactive Publication Date: 2014-02-12BEIJING VENTUREPHARM BIOTECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
BEIJING VENTUREPHARM BIOTECH
Publication Date
2014-02-12
Estimated Expiration
Not applicable · inactive patent
Patent Text Reader

Abstract

The invention belongs to the field of pharmaceutical preparations and relates to a compound syrup preparation composition for preparing dextromethorphan or physiologically acceptable salts thereof and guaifenesin. The compound syrup preparation composition consists of cane sugar, sodium benzoate, ethylparaben, citric acid, sodium citrate, pigments and essence. The compound preparation can be used for effectively relieving cough-related symptoms caused by respiratory tract infection and bronchitis, has a synergistic effect of medicines and also can be used for effectively and conveniently controlling the administration amount of a patient, and greatly reducing the children administration difficulty. Therefore, the dosage form has the characteristics that the compound preparation is high in dispersity, fast in absorption and fast in effectiveness after being taken by the patient, and the bioavailability of the medicine is improved.
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Description

technical field

[0001] The invention belongs to the field of pharmaceutical preparations, and relates to a method for preparing a compound syrup preparation of dextromethorphan or a physiologically acceptable salt thereof and guaifenesin. Background technique

[0002] Dextromethorphan is a centrally acting antitussive drug that acts by inhibiting the cough center in the medulla medulla. This product is the dextro-isomer of morphine-like levomorphan methyl ether. It exerts central antitussive effect by inhibiting the medullary cough center. Compared with codeine, its antitussive intensity is equal or slightly stronger, and it has no analgesic effect. Effect, long-term application has no tolerance and addiction. It does not have the side effect of inhibiting respiration, is well absorbed orally, takes effect within 15-30 minutes, and can maintain the effect for 3-6 hours. The concentration of the original drug in plasma is very low. The drug effect of dextromethorphan is pro...

Claims

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