A strong medicine for preventing and treating post-stroke depression and its preparation method

A technology for stroke and depression, applied in the field of medicine and health, can solve problems such as induced hypertension and stroke, and achieve the effects of low production cost, simple process, reasonable and innovative formula

Inactive Publication Date: 2015-11-18
LIUZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, moclobemide and serotonin reuptake inhibitors (SSRI) such as fluoxetine and tiparoxetine are widely used in the treatment of PSD by Western medicine. They have a quick effect and can treat depression and anxiety at the same time, but they have the effect of inducing hypertension. danger and further stroke

Method used

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  • A strong medicine for preventing and treating post-stroke depression and its preparation method
  • A strong medicine for preventing and treating post-stroke depression and its preparation method
  • A strong medicine for preventing and treating post-stroke depression and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Embodiment 1 syrup

[0058] Take 3kg of gourd tea, 2kg of Yejiao vine, 2kg of Yulang umbrella, 3kg of big red diamond, and 0.5kg of white peony root. Add water to extract the above-mentioned 5 medicinal materials twice, the amount of water added twice is 10 times and 8 times of the total weight of the medicinal materials respectively, the extraction time of the two times is 2 hours and 1 hour respectively, the extracts are combined, filtered, and the filtrate is concentrated to 80 An extract with a relative density of 1.10 at °C. Adding syrup auxiliary materials sucrose, sorbic acid and water into the extract and stirring evenly to prepare the syrup.

Embodiment 2

[0059] Example 2 tablet

[0060] Take 7kg of Gourd Tea, 5kg of Yejiaovine, 5kg of Yulang Umbrella, 8kg of Big Red Diamond, and 2kg of Radix Paeoniae Alba. The above five herbs were reflux extracted with 40% ethanol for 3 times, the amount of ethanol each time was 10 times, 8 times, and 4 times the total amount of the herbs, and the extraction time was 3 hours, 2 hours, and 1 hour respectively, and the extracts were combined. After filtering, the filtrate is concentrated to an extract with a relative density of 1.25 at 60°C, and supplementary materials such as starch, ethanol and talc are added to prepare tablets.

Embodiment 3

[0061] Embodiment 3 mixture

[0062] Take 4kg of gourd tea, 3.5kg of Yejiao vine, 3kg of Yulang umbrella, 3.5kg of big red diamond, and 1kg of white peony root. Add water to extract the above five medicinal materials for 3 times. The amount of water added three times is equivalent to 12 times, 8 times, and 6 times the total weight of the medicinal materials. The extraction time is 3 hours, 2 hours, and 1 hour respectively. Combine the extracts and filter When the filtrate is concentrated to 70°C, the relative density is 1.20, add ethanol to make the alcohol content 40%, let it stand for 24 hours, filter, and the filtrate is concentrated to the extract with a relative density of 1.10 when the filtrate is concentrated to 70°C , add purified water until the total weight is 3 times of the total weight of the medicinal materials, fill it, add mixture auxiliary materials sucrose, ethyl ester, water and sorbic acid and stir evenly to prepare the mixture.

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PUM

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Abstract

The invention discloses a Zhuang nationality medicine for preventing and curing post-stroke depression and a preparation method thereof. The composition is prepared from five raw materials including desmodium triquetrum, tuber fleeceflower stem, millettia pulchra(Dunn)Kurz var.laxior(Dunn)Z.Wei, kadsura heteroclita(Roxb.)Craib and white paeony root. The invention further provides a preparation method of the Zhuang nationality medicine for preventing and curing post-stroke depression. The Zhuang nationality medicine provided by the invention has the effects of clearing away heat and toxic materials, dispelling wind and eliminating dampness, and activating and harmonizing qi and blood, so as to ensure dragon road smoothness and normal conduction and achieve a physiological status of qi-blood reconciling and three-qi synchronization. The Zhuang nationality medicine has a significant effect of preventing and curing the post-stroke depression.

Description

technical field [0001] The invention relates to the field of medicine and health, in particular to a strong medicine for preventing and treating post-stroke depression and a preparation method thereof. Background technique [0002] Post-stroke depression (PSD) is a complex affective disorder that occurs after stroke and includes a variety of mental and physical symptoms. The main manifestations are persistent depression, slow thinking, disordered thinking content, and decreased volitional activity, which cause a series of clinical symptoms of multiple systems such as gastrointestinal tract, cardiovascular system, and respiratory system, and even some patients have behaviors such as world-weariness and suicide. [0003] A large number of clinical reports suggest that the incidence of post-stroke depression is relatively high. Foreign literature reports that the incidence is 25%-79%, most of which are 40%-50%. And studies have shown that post-stroke depression has a significa...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61P9/10A61P25/24
Inventor 王晓源
Owner LIUZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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