Carboxymethylated Derivatives of Exopolysaccharides of Trichodia granulosa and Their Application in the Preparation of Anti-renal Failure Drugs

A technology of extracellular polysaccharides and Trichomonas granulosa, applied in the direction of drug combination, urinary system diseases, etc., to achieve the effect of simple method, reducing MDA content, and overcoming gastric discomfort
CN103755827BInactive Publication Date: 2015-12-09HEFEI UNIV OF TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HEFEI UNIV OF TECH
Publication Date
2015-12-09
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a lachnum exopolysaccharides carboxymethylation derivative and an application thereof in preparation of chronic renal failure-resistant medicines. The lachnum exopolysaccharides carboxymethylation derivative is characterized in that lachnum exopolysaccharides with the strain collection number of CCTCC No: M 2011196 are subjected to chloroacetic acid carboxymethylation modification to obtain the lachnum exopolysaccharides carboxymethylation derivative, and the lachnum exopolysaccharides carboxymethylation derivative in an effective dose and medical auxiliary materials are prepared into tablets and capsules for clinical use according to a conventional preparation method in pharmaceutics due to the effect of obviously resisting chronic renal failure. The pharmacodynamic experiment proves that the exopolysaccharides and carboxymethylation derivative has an obvious effect of resisting chronic renal failure and does not have a toxic or side effect, and the preparation method is simple and economic.
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Description

technical field

[0001] The present invention belongs to the application of the exopolysaccharide of Trichodia granulosa in the field of medicine, and specifically relates to the carboxymethylated derivative of Trichodia granulosa exopolysaccharide and its preparation of anti-renal failure medicine. the use of. Background technique

[0002] Modern medicine believes that the kidney is an important excretory organ of the human body. Its main function is to filter and form urine and discharge metabolic waste, and to regulate the electrolyte and acid-base balance in the body. Chronic renal failure is a progressive damage to the kidneys caused by various primary kidney diseases or secondary to other diseases. Syndrome has become a global public health problem. Hemodialysis and kidney transplantation can treat chronic renal failure and end-stage renal disease, but they are expensive and difficult to popularize. Clinically used drugs are usually Haikun Shenxi Capsules, Niaoduqing ...

Claims

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