Preparation method of slow-release ivermectin injection

Abstract

The invention relates to a slow-release ivermectin injection for expelling and treating parasites in livestock bodies and a preparation method thereof. The slow-release ivermectin injection mainly overcomes the disadvantages of complex production process, inconvenience in application, inaccurate dosage, poor insect repellent effects and the like of ivermectin preparation drugs in the prior art, the slow-release ivermectin injection mainly comprises ivermectin, ethyl cellulose, ethyl oleate, glycerolformal and benzyl alcohol, and the preparation method is as follows: weighing the prescription dose of the ivermectin and the ethyl cellulose to dissolving in the prescription dose of the benzyl alcohol and the ethyl oleate, using the glycerolformal to fix to a constant volume, and sterilizing with wet and hot steam at 100 DEG C for 30 minutes. The slow-release ivermectin injection has the advantages of simple production process, stable quality, simple drug application operation, accurate dosage, and significant insect repellent effects.

Description

technical field [0001] The invention relates to an ivermectin sustained-release injection for expelling parasites in livestock and a preparation method thereof. Background technique [0002] There are many kinds of parasitic diseases and they are widely distributed. They are very common and serious diseases of livestock. They seriously affect the production of meat, milk and eggs, the quality of fur and the working ability of draft animals. Some zoonotic parasitic diseases also directly harm human health. Therefore, parasitic diseases not only hinder the development of animal husbandry and cause huge economic losses, but also are the most common and serious public health problems. In the past 10 years, due to insufficient investment in science and technology and funds, there are not many new technologies suitable for production, and there are basically no major breakthroughs and innovations in parasitic disease control technology. Chemical control is still the leading contr...

AI Technical Summary

Problems solved by technology

Due to the increasingly serious drug resistance and the defects of the original antiparasitic drugs, the development of new drugs is a very important issue in the chemical control of parasitic diseases, and it is also the basis for promoting chemical control of parasites. However, the development cycle of new compounds is long and the cost is high. Therefore, the development of new preparations based on existing drugs has become one of the focuses of new drug research