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Compositions for enhancing nail health

A composition and nail technology, which can be used in manicure, drug combination, cosmetic preparations, etc., and can solve time-consuming problems

Inactive Publication Date: 2014-08-13
ALLERGAN INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The problem with current treatments used to improve nail health is that they are mostly cosmetic in nature, mostly ineffective, are often absorbed systemically (such as biotin and silicon) and are time consuming

Method used

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  • Compositions for enhancing nail health
  • Compositions for enhancing nail health
  • Compositions for enhancing nail health

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[1193] A study was conducted to compare cyclosporine A with emulsion BID.

[1194] ●2 nails suffering from brittle nail syndrome (BNS)

[1195] ● 2 most "normal" nails

[1196] ●One treatment and one no treatment

[1197] ●N=24 (12 people in each treatment group)

[1198] ●6 monthly follow-ups

[1199] ●1°-Severity Physician's Comprehensive Assessment (PGA)

[1200] ●2°-Multiple secondary metrics and photos

[1201]

[1202] 2° evaluation

[1203] -Nail length growth

[1204] -Physician Improvement Level (PGIA)

[1205] -Fragility / fracture (BNS)

[1206] -Lamellar transverse division

[1207] -Uplift

[1208] -Vertical split

[1209] -thickness

[1210] -Texture / smoothness

[1211] -luster

[1212] -Patient reported results and satisfaction

[1213] Inclusion criteria

[1214] Must have brittle armor based on:

[1215] -Have at least two signs and symptoms of brittle nails on the target nail

[1216] -Severe signs (one or more) on each target nail

[1217] (i) Rough face mask (rough surface)

[1218] (i...

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PUM

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Abstract

The present invention is directed to compositions and methods for enhancing the health of nails and cuticles in a mammal, including humans. The compositions may be administered topically to the nail bed, nail matrix and cuticle in an amount effective to enhance nail health. The composition is also effective in strengthening and growing nails.

Description

[0001] Related applications [0002] This patent application claims the rights of the U.S. Provisional Patent Application Serial No. 61 / 543,758 filed on October 5, 2011, which is incorporated herein by reference. Technical field [0003] This application relates to a composition for improving the health and growth of nails and stratum corneum. Background of the invention [0004] Nails including toenails and fingernails are mainly composed of keratin. Fingernails and toenails are living tissue. The nail is formed in a pocket of skin that has grown inward and is called the nail matrix. This area produces nails and is also called nail root. The outer layer of the matrix contains specialized cells that form keratin that grows in the form of nail plates. [0005] Nail plates are commonly called fingernails or toenails. [0006] The nail bed is the finger tissue or toe tissue that supports the nail. Nails continue to grow throughout a person's life, with an average growth rate of about...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/92A61K8/06A61Q3/00
CPCA61K8/062A61Q3/00A61K2800/78A61K8/922A61K8/64A61P17/00A61P17/06A61P29/00A61P31/10
Inventor J·G·沃尔特
Owner ALLERGAN INC
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