Compositions for enhancing nail health
a technology of compositions and nail health, applied in the field of compositions for enhancing nail health, can solve the problems of lack of thickness and/or poor nail growth, poor nail growth, brittle nail syndrome, etc., and achieve the effects of improving nail health, reducing nail damage, and reducing nail damag
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[1241]A study was conducted to compare Cyclosporine A vs. an emulsion BID. (FIGS. 1-6)[1242]2 nails with Brittle Nail Syndrome (BNS)[1243]2 best most “normal” nails[1244]one treated and one not[1245]N=24 (12 per treatment arm)[1246]6 Monthly Visits[1247]1°—Physician Global Assessment of Severity (PGA) (FIGS. 8-10)[1248]2°—Multiple Secondary Measures and Photos
2° Assessments (FIGS. 7, 11-59)
[1249]Nail growth in length[1250]Physician grade of improvement (PGIA)[1251]Fragility / Breakage (BNS)[1252]Lamellar Transverse Splitting-Onychoschizia[1253]Ridging[1254]Longitudinal Splitting[1255]Thickness[1256]Texture / smoothness[1257]Shininess[1258]Patient Reported Outcomes and Satisfaction
Inclusion Criteria
[1259]Must have brittle nails based on[1260]at least two signs and symptoms of brittle nails on the target nails[1261]severe signs (one or more) on each target nail[1262](i) Trachyonychia (surface roughness)[1263](ii) Lamellar onychoschizia (horizontal layering / peeling)[1264](iii) Longitudinal...
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