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Compositions for enhancing nail health

a technology of compositions and nail health, applied in the field of compositions for enhancing nail health, can solve the problems of lack of thickness and/or poor nail growth, poor nail growth, brittle nail syndrome, etc., and achieve the effects of improving nail health, reducing nail damage, and reducing nail damag

Inactive Publication Date: 2013-06-20
ALLERGAN INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The patent describes a skincare product that can be applied to the nails and cuticle to improve their health. The product can make the nails stronger, smoother, and help with brittle nail syndrome. The product can be applied everyday, and there are different amounts of product that can be used depending on the frequency of application. The product can come in a kit with a vial and an applicator.

Problems solved by technology

Poor nail and cuticle health can result in Brittle Nail Syndrome.
In addition, Brittle Nail Syndrome can also result in nail fragility, lack of thickness and / or poor nail growth.
The treatment of fingernail and toe nail problems due to various conditions such as anemia, vitamin or mineral deficiency, onycohrrhexis, kidney and liver disorders, psoriasis, vascular disease (e.g., Raynaud's disease) and heart disease often result in poor nail growth, vertical trenches, pitting, cracking, horizontal lines, lack of thickness and strength, lack of smoothness, tendency to tear and other symptoms of Brittle Nail Syndrome.
The problem with current treatments for improving nail health is that they are mainly cosmetic in nature, largely ineffective, are generally taken systemically (e.g., biotin and silicon) and time consuming.

Method used

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  • Compositions for enhancing nail health
  • Compositions for enhancing nail health
  • Compositions for enhancing nail health

Examples

Experimental program
Comparison scheme
Effect test

example 1

[1241]A study was conducted to compare Cyclosporine A vs. an emulsion BID. (FIGS. 1-6)[1242]2 nails with Brittle Nail Syndrome (BNS)[1243]2 best most “normal” nails[1244]one treated and one not[1245]N=24 (12 per treatment arm)[1246]6 Monthly Visits[1247]1°—Physician Global Assessment of Severity (PGA) (FIGS. 8-10)[1248]2°—Multiple Secondary Measures and Photos

2° Assessments (FIGS. 7, 11-59)

[1249]Nail growth in length[1250]Physician grade of improvement (PGIA)[1251]Fragility / Breakage (BNS)[1252]Lamellar Transverse Splitting-Onychoschizia[1253]Ridging[1254]Longitudinal Splitting[1255]Thickness[1256]Texture / smoothness[1257]Shininess[1258]Patient Reported Outcomes and Satisfaction

Inclusion Criteria

[1259]Must have brittle nails based on[1260]at least two signs and symptoms of brittle nails on the target nails[1261]severe signs (one or more) on each target nail[1262](i) Trachyonychia (surface roughness)[1263](ii) Lamellar onychoschizia (horizontal layering / peeling)[1264](iii) Longitudinal...

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Abstract

The present invention is directed to compositions and methods for enhancing the health of nails and cuticles in a mammal, including humans. The compositions may be administered topically to the nail bed, nail matrix and cuticle in an amount effective to enhance nail health. The composition is also effective in strengthening and growing nails.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application claims the benefit of U.S. Provisional Ser. No. 61 / 543,758 filed on Oct. 5, 2011, which is incorporated by reference herein.FIELD OF THE INVENTION[0002]The present application is directed to compositions for enhancing nail and cuticle health and growth.BACKGROUND OF THE INVENTION[0003]Nails, including toenails and fingernails, are primarily composed of the protein keratin. Fingernails and toenails are living tissue. The nail is formed in a pocket of skin which has grown inward and is called the nail matrix. This area generates the nail and is also called the root of the nail. The outer layer of the matrix contains specialized cells that create the keratin that grows out as the nail plate.[0004]The nail plate is the commonly referred to as a fingernail or toenail.[0005]The nail bed is the finger tissue or toe tissue that supports the nail. Nails grow continuously throughout a person's life, growing approximately at an avera...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K38/13A61K31/407
CPCA61K8/42A61K45/06A61K8/062A61K38/13A61Q3/00A61K31/5575A61K31/407A61K8/361A61K8/64A61K8/492A61K9/107A61K2300/00A61P17/00A61P17/06A61P19/02A61P29/00A61P3/02A61P31/04A61P31/10A61P37/06A61P43/00A61Q3/02
Inventor WALT, JOHN G.
Owner ALLERGAN INC
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