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Application of Xinhuang tablet traditional Chinese medicinal ingredients on indometacin in liver, kidney, stomach and intestine poisonousness reduction aspect

A technology of indomethacin and Xinhuang tablets, which can be applied to medical preparations containing active ingredients, pharmaceutical formulations, organic active ingredients, etc., can solve problems such as reports on the research and application of the detoxification mechanism of Xinhuang tablets that have never been seen. , to achieve the effect of wide application prospects

Inactive Publication Date: 2015-02-11
XIAMEN TRADITIONAL CHINESE MEDICINE
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AI Technical Summary

Problems solved by technology

[0010] In the past, Xinhuang Tablets were mainly used for clearing away heat and detoxification, promoting blood circulation and removing blood stasis, reducing swelling and relieving pain. There have been no reports on the research and application of Xinhuang Tablets on the mechanism of detoxification

Method used

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  • Application of Xinhuang tablet traditional Chinese medicinal ingredients on indometacin in liver, kidney, stomach and intestine poisonousness reduction aspect
  • Application of Xinhuang tablet traditional Chinese medicinal ingredients on indometacin in liver, kidney, stomach and intestine poisonousness reduction aspect
  • Application of Xinhuang tablet traditional Chinese medicinal ingredients on indometacin in liver, kidney, stomach and intestine poisonousness reduction aspect

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Embodiment Construction

[0016] In order to make the purpose, technical scheme and advantages of the present invention clearer, the application of the traditional Chinese medicine ingredients in Xinhuang Tablets in pharmaceuticals will be further illustrated below through the pharmacological experiment results of Xinhuang Tablets.

[0017] 1 Purpose of the test

[0018] To study the attenuating effect and mechanism of Chinese medicinal ingredients in Xinhuang Tablets on the toxicity of indomethacin.

[0019] Test product and control drug

[0020] 2.1 Test drugs

[0021] Drug name: Xinhuang Tablets, the traditional Chinese medicine ingredients mainly include swollen joint wind, notoginseng, artificial bezoar, pig bile ointment, Xiao Fantian flower, pearl layer powder, buffalo horn concentrated powder, red yeast rice, among which, the usage and dosage of each traditional Chinese medicine ingredient are respectively for:

[0022] Panax notoginseng: [Usage and Dosage] 3-9g; grind into powder and swallo...

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Abstract

The invention discloses an application of Xinhuang tablet traditional Chinese medicinal ingredients on indometacin in a liver, kidney, stomach and intestine poisonousness reduction aspect. The Xinhuang tablet traditional Chinese medicinal ingredients comprise glabrous sarcandra herb, pseudo-ginseng, calculus bovis factitius, a porcine bile paste, urena lobata l, a pearl layer powder, a cornu bubali concentrated powder, and red kojic rice. Pharmacological experiments find out that the Xinhuang tablet traditional Chinese medicinal ingredients have the poisonousness reduction effect on indometacin; and with the utilization of the action mechanism, Xinhuang tablets are used in new drug development, and have wide application prospects.

Description

technical field [0001] The invention relates to the application of the traditional Chinese medicine components of Xinhuang Tablets to indomethacin in attenuating liver, kidney, stomach and intestines. Background technique [0002] The main ingredients of Xinhuang Tablets are Zhongjiefeng, Panax notoginseng, artificial bezoar, pig bile ointment, Xiao Fantian flower, nacre powder, buffalo horn concentrated powder, red yeast rice, etc. The main functions are to clear away heat and detoxify, promote blood circulation and remove blood stasis, and reduce swelling pain relief. It is used for sore throat, toothache, arthralgia, hypochondriac pain, jaundice, and nameless swelling and poisoning caused by heat toxin and blood stasis. [0003] As a western medicine, indomethacin is a non-steroidal anti-inflammatory drug with anti-inflammatory, antipyretic and analgesic effects. This drug can inhibit cyclooxygenase and reduce the synthesis of prostaglandins to achieve anti-inflammatory ...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61P1/16A61P13/12A61P1/04A61P1/14A61P29/00A61K35/32A61K35/413A61K35/618A61K31/405
CPCA61K9/20A61K35/32A61K35/413A61K35/618A61K36/06A61K36/185A61K36/258A61K2300/00
Inventor 南淑华刘静墙世发申秀萍郑珊珊杨惠婉王杰包侠萍关斌胡金芳王春凤赖志成阳丽华肖顺彪
Owner XIAMEN TRADITIONAL CHINESE MEDICINE
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