Promoting fibroblast transdifferentiation into adipocytes using defined cytokine combinations
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACAD OF SCI
- Publication Date
- 2017-04-05
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention relates to a cell transdifferentiation-inducing cytokine composition and a method for culturing cell transdifferentiation, in particular to a cytokine composition for promoting the transdifferentiation of fibroblasts into adipocytes and using the composition to promote the transdifferentiation of fibroblasts into fat Cell culture method. Background technique
[0002] The cause of obesity is that when the energy in the body is out of balance and the energy intake is greater than the energy consumed, the excess energy is mainly stored in the form of fat, and the weight of fat increases, leading to the occurrence of obesity. Fat is mainly stored in the adipose tissue of the body, and the increase of adipose tissue is mainly manifested in the increase of the volume of fat cells and the increase of the number of fat cells. However, the volume of fat cells has a certain limit, and it is impossible to increase indefinitely, so excessive energy ...