Pharmaceutical composition for treating liver depression and spleen deficiency syndromes as well as preparation method and application of pharmaceutical composition

A technology of liver depression and spleen deficiency and composition, which is applied in the field of drugs for treating liver depression and spleen deficiency, can solve the problems of not being able to obtain effective curative effects, and achieve the effects of improving the degree of hepatic steatosis, effective liver function, and improving clinical symptoms

Active Publication Date: 2015-02-25
BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem solved by the present invention is: none of the current prescriptions for the treatment of NAFLD by traditional Chinese medicine can obtain effective curative effect.

Method used

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  • Pharmaceutical composition for treating liver depression and spleen deficiency syndromes as well as preparation method and application of pharmaceutical composition
  • Pharmaceutical composition for treating liver depression and spleen deficiency syndromes as well as preparation method and application of pharmaceutical composition
  • Pharmaceutical composition for treating liver depression and spleen deficiency syndromes as well as preparation method and application of pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0046] Astragalus 10g, fried Atractylodes macrocephala 10g, raw barley 10g, salvia miltiorrhiza 20g, Cyperus cyperi 5g, Bupleurum 5g, capillary 5g, Polygonum cuspidatum 5g, corrugated seed 10g, verbena 10g, cassia seed 10g, raw hawthorn 20g and Shuihonghuazi 15g , take each medicinal material raw material (the above-mentioned medicine commercially purchases from Beijing Kangrentang Pharmaceutical Co., Ltd.), mix them, add water to submerge and exceed more than 1 / 3 of the medicinal surface, soak for 35 minutes, after that, first boil with high heat, and then Use slow fire to decoct for about 20 minutes until the remaining medicinal liquid is about 200ml, repeat the above decocting process twice, mix the obtained medicinal juice and divide it into two parts, each of which is about 200ml, and set aside (take one in the morning and one in the evening).

preparation example 2

[0048] Astragalus 20g, fried Atractylodes macrocephala 15g, raw barley 15g, salvia miltiorrhiza 10g, Cyperus cyperi 8g, Bupleurum 10g, capillary wormwood 10g, knotweed 10g, corrugated seed 20g, verbena 15g, cassia seed 15g, raw hawthorn 15g and water safflower seeds 10g , take each medicinal material raw material (the above-mentioned medicine commercially purchases from Beijing Kangrentang Pharmaceutical Co., Ltd.), mix them, add water to submerge and exceed more than 1 / 3 of the medicinal surface, soak for 35 minutes, after that, first boil with high heat, and then Use slow fire to decoct for about 20 minutes until the remaining medicinal liquid is about 200ml, repeat the above decocting process twice, mix the obtained medicinal juice and divide it into two parts, each of which is about 200ml, and set aside (take one in the morning and one in the evening).

preparation example 3

[0050] Astragalus 30g, fried Atractylodes macrocephala 20g, raw barley 25g, salvia 30g, Cyperus cyperi 12g, Bupleurum 12g, capillary wormwood 12g, knotweed 12g, corrugated seed 30g, verbena 20g, cassia seed 20g, raw hawthorn 20g and water safflower seeds 20g , weigh the raw materials of each medicinal material (the above-mentioned drugs are commercially purchased from Beijing Kang Ren Tang Pharmaceutical Co., Ltd.), mix them, add water to submerge and exceed more than 1 / 3 of the drug surface, soak for 35 minutes, and then boil with high heat , and then use slow fire to decoct for about 20 minutes until the remaining medicinal liquid is about 200ml, repeat the above decoction process twice, mix the obtained medicinal juice and divide it into two parts, each part is about 200ml, and set aside (take one in the morning and one in the evening).

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Abstract

The invention relates to a medicine for treating liver depression and spleen deficiency syndromes and in particular provides a pharmaceutical composition for treating liver depression and spleen deficiency syndromes as well as a preparation method and application thereof. The pharmaceutical composition for treating the liver depression and spleen deficiency syndromes contains the following components: astragalus, processed bighead atractylodes rhizome, raw coix seed, salviae miltiorrhizae, rhizoma cyperi, radix bupleuri, oriental wormwood, polygonum cuspidatum, concha arcae, verbena, semen cassiae, raw hawthorn and fructus polygoni orientalis. The pharmaceutical composition for treating liver depression and spleen deficiency syndromes has the following effects when applied to a patient suffering from non-alcoholic type fatty liver disease (NAFLD): clinical symptoms and signs of the NAFLD patient are obviously alleviated; liver function and blood lipid parameters of the patient can be safely and effectively reduced, and the effects of protecting the liver, lowering transaminase and lowering lipid are realized; and hepatic steatosis degree of the patient is obviously reduced.

Description

technical field [0001] The invention relates to a medicine for treating liver stagnation and spleen deficiency, in particular to a medicine composition for treating nonalcoholic fatty liver disease, its medicament and their preparation method. Background technique [0002] Non-alcoholic fatty liver disease (NAFLD) is a clinicopathological syndrome characterized by steatosis and fat accumulation in hepatic parenchymal cells without a history of excessive alcohol consumption. One of the focuses of medical research. In recent years, with the improvement of living standards and changes in living habits and diet structure in my country, the incidence of non-alcoholic fatty liver disease is on the rise, and has become a common and frequently-occurring disease in gastroenterology. [0003] At present, western medical treatment is mainly based on lifestyle intervention (including diet and exercise), and there is no specific drug for non-alcoholic fatty liver disease. C, E, acetylc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61K9/16A61K9/00A61P1/16A61K35/618
CPCA61K9/0095A61K35/618A61K36/233A61K36/28A61K36/284A61K36/481A61K36/482A61K36/537A61K36/70A61K36/704A61K36/734A61K36/85A61K36/8905A61K36/8994A61K2236/331A61K2236/53A61K2300/00
Inventor 张声生周滔郁强
Owner BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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