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Traditional Chinese medicine composition for reducing fat and preparation thereof

A pharmaceutical preparation and composition technology, applied in the field of traditional Chinese medicine, can solve problems such as upper abdominal fullness and discomfort

Active Publication Date: 2015-04-08
山东京御堂制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in clinical use, a small number of patients will have side effects such as upper abdominal fullness and discomfort after taking it.

Method used

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  • Traditional Chinese medicine composition for reducing fat and preparation thereof
  • Traditional Chinese medicine composition for reducing fat and preparation thereof
  • Traditional Chinese medicine composition for reducing fat and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The preparation of embodiment 1 Chinese medicine composition

[0018] (1) 11g of Alisma medicinal material is dried and pulverized into fine powder respectively, and passed through a 200-mesh sieve;

[0019] (2) Decoct 45g of Pueraria lobata, 17g of hawthorn, 11g of Polygonum multiflorum and 16g of Angelica sinensis with 8 times the amount of water, each time for 1.5 hours, filter, combine the filtrates, and concentrate to 60°C when the relative density is 1.10~ 1.20 extract; add ethanol until the alcohol content reaches 70%, stir evenly, let stand, take the supernatant to recover ethanol, dry and pulverize to obtain a fine powder to obtain the Chinese medicine composition.

Embodiment 2

[0020] The preparation of embodiment 2 Chinese medicine composition

[0021] (1) Dry and pulverize 11g of Alisma medicinal material into fine powder respectively; pass through a 200-mesh sieve;

[0022] (2) Add 43g of pueraria lobata, 16g of hawthorn, 13g of Polygonum multiflorum and 17g of Angelica sinensis with 8 times the amount of water and decoct three times, each time for 1.5 hours, filter, combine the filtrates, and concentrate to 60 °C when the relative density is 1.10~ 1.20 extract; add ethanol until the alcohol content reaches 70%, stir evenly, let stand, take the supernatant to recover ethanol, dry and pulverize to obtain a fine powder to obtain the Chinese medicine composition.

Embodiment 3

[0023] Embodiment 3 traditional Chinese medicine composition is to the blood fat effect of feeding high-fat feed rats

[0024] Rat AS model was established by stimulating inflammatory response with high-fat diet plus intraperitoneal injection of VD3 and ovalbumin. The modeling time is 1 and a half months. The specific steps are as follows: After one week of adaptive feeding, the rats were randomly divided into groups (8 rats in each group), which were respectively blank group (normal state, NS), model group and each administration group. Give high-fat feed (containing 1% cholesterol, 0.2% pig bile salt, 10% lard, 10% egg yolk powder, 78.8% basic feed). After grouping, except the NS group, rats in other groups were intraperitoneally injected with VD 3 600,000 IU / kg, the NS group was given an equal volume of normal saline; the next day, the rats were immune-injured (dissolve ovalbumin in normal saline, take an equal amount of ovalbumin solution and complete Freund's adjuvant, ...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for reducing fat and a preparation thereof. The traditional Chinese medicine composition is prepared from the following materials in percentage by weight: 30-60 percent of radix puerariae, 10-40 percent of fructus crataegi, 10-30 percent of rhizoma alismatis, 10-30 percent of polygonum multiflorum and 10-30 percent of angelica sinensis. The medicine composition disclosed by the invention can be prepared into a suitable oral preparation for reducing fat as needed by using pharmaceutically acceptable auxiliary materials.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for lipid-lowering and a preparation thereof, in particular to a traditional Chinese medicine composition such as kudzu root for lipid-lowering treatment, and belongs to the field of traditional Chinese medicine. Background technique [0002] Cardiovascular disease has become the first cause of death in urban and rural populations in my country. Cardiovascular disease in China is characterized by a high incidence of stroke and a low incidence of coronary heart disease. However, the incidence and mortality of coronary heart disease have gradually increased in the past 20 years; In large cities with rapid economic development, such as Beijing, the monitoring results show that the incidence of hemorrhagic stroke showed a significant downward trend from 1984 to 1999, while the incidence of ischemic stroke increased significantly, indicating that atherosclerosis is the main cause. The inciden...

Claims

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Application Information

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IPC IPC(8): A61K36/884A61P3/06
CPCA61K9/1652A61K36/232A61K36/488A61K36/704A61K36/734A61K36/884A61K2236/15A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 肖军平吴永忠周朝忠陈梁康兴东
Owner 山东京御堂制药有限公司
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