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A kind of traditional Chinese medicine composition with antitumor effect

A technology of anti-tumor effect and composition, which is applied in the directions of anti-tumor drugs, drug combinations, and medical preparations containing active ingredients, etc., can solve problems such as large toxic and side effects, low treatment efficiency, and poor anti-tumor drug effects.

Active Publication Date: 2017-07-28
赖德禄
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a kind of Chinese medicine composition with antitumor effect which can effectively remove tumor cells and has low toxic and side effects. low efficiency

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] 1. Raw material formula:

[0076] Dracaena 500g, Saffron 500g, Dannanxing 750g, Prunella vulgaris 750g

[0077] Scrophulariaceae 1000 grams, rock sugar grass 1000 grams, southern snake stick 3000 grams;

[0078] 2. Preparation method:

[0079] Take the saffron, dragon's blood and 1000 grams of Nanshe sticks in the above formula, dry them, and crush them into 200 mesh mixed fine powder for later use. The other 2000 grams of Nanshe sticks are mixed with Bingtangcao, Prunella vulgaris, Scrophulariaceae and Dannanxing Heat and extract 3 times, the amount of water added for the 3 extractions is 65 kg, 46 kg and 39 kg respectively, the time of the 3 extractions is boiling for 3 hours, 2 hours and 2 hours respectively, the 3 extracts are filtered respectively and the filtrate is combined, the filtrate Heat and concentrate to 60°C for heat measurement, the relative density of the thick paste is 1.08, take the thick paste and mix the fine powder, mix evenly, dry, grind to 60 m...

Embodiment 2

[0081] 1. Raw material formula:

[0082] Dracaena 1000g saffron 1000g Dannanxing 1250g Prunella vulgaris 1250g

[0083] Scrophulariaceae 1500 grams, rock sugar grass 1500 grams, southern snake stick 4000 grams;

[0084] 2. Preparation method:

[0085] Take the saffron, dragon's blood and 1300 grams of Nanshe sticks in the above formula, dry them, and crush them into 200 mesh mixed fine powder for later use. The other 2700 grams of Nanshe sticks are mixed with Bingtangcao, Prunella vulgaris, Scrophulariaceae and Dannanxing Heating and extracting 3 times, the amount of water added for the 3 extractions is 82 kg, 66 kg and 49 kg respectively, the time of the 3 extractions is boiling for 3 hours, 2 hours and 2 hours respectively, the 3 extractions are filtered respectively and the combined filtrate, the filtrate Heat and concentrate to 60°C for heat measurement, the relative density of the thick paste is 1.10, take the thick paste and mixed fine powder, mix evenly, dry, grind to...

Embodiment 3

[0087] 1. Raw material formula:

[0088] Dracaena 600g, saffron 700g, Dannanxing 1100g, Prunella vulgaris 1100g

[0089] Scrophulariaceae 1700 grams, rock sugar grass 1700 grams, southern snake stick 3400 grams;

[0090] 2. Preparation method:

[0091] Take the saffron and dragon's blood in the above formula and dry them, crush them into 300 mesh mixed fine powder for later use, and heat and extract the other Nanshe sticks together with Bingtangcao, Prunella vulgaris, Scrophulariaceae and Dannanxing for 3 times, and extract for 3 times The amount of water added is 80 kg, 72 kg and 54 kg respectively, and the three extraction times are boiled for 3 hours, 2 hours and 2 hours respectively. The relative density of the thick paste is 1.09. The thick paste is mixed with the pharmaceutical excipients mixed with fine powder and conventional granules, prepared into granules according to the conventional preparation method of granules, and dried so that every 5 grams of granules cont...

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Abstract

The invention discloses a traditional Chinese medicine composition with an anti-tumor effect. The composition is prepared from the following raw materials: dragon's blood, stigma croci, arisaema cum bile, prunella vulgaris, radix scrophulariae, sweet broomwort herbs and amorphophallus dunnii. The raw materials are prepared into dosage forms in pharmacy, comprising granules, capsules or tablets. To verify the pharmacology effect of the composition, the capsules, namely the anti-tumor capsules, are researched through pharmacological experiments, and the researched result proves that the anti-tumor capsules have an obvious anti-tumor effect in the body, and have no adverse effects on obviously changing the weight of mice. For the composition, anti-tumor in-vitro experiments are also carried out, and the experiment result indicates that the anti-tumor capsules have a certain inhibiting effect on culture in vitro cells of human hepatoma cell lines 7404 and ascitic tumor cell lines S180 of the mice. Compared with cyclophosphamide, the cyclophosphamide is a traditional anti-cancer drug but has the side effects of causing mutagenesis, teratogenesis and the like, but the anti-tumor capsules have better in-vitro anti-tumor effect and higher safety.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition with antitumor effect. The traditional Chinese medicine composition is composed of natural plant Chinese herbal medicines. The commercial name of capsules prepared from the traditional Chinese medicine composition is Yi'ai Capsule, which belongs to the technical field of medicine preparation. Background technique [0002] Tumors are a large class of complex diseases that seriously threaten human health. At present, the etiology and pathology of tumors are still in the stage of exploration, and the clinical treatment method is mainly surgery, which achieves the purpose of treatment by resecting the tumor. However, the particularity of tumors lies in the fact that tumor cells are metastatic and can metastasize in the body. This is the greatest harm of tumors to the human body. In order to prevent the metastasis of tumor cells, clinically, after surgical resection of tumors, radiotherapy ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61P35/00
CPCA61K36/536A61K36/80A61K36/808A61K36/88A61K36/888A61K36/8884A61K36/896A61K2236/15A61K2236/331A61K2236/39A61K2300/00
Inventor 赖德禄
Owner 赖德禄
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