Transcatheter left atrial appendage plugging system

Abstract

The invention relates to a transcatheter left atrial appendage plugging system. The system is composed of an inner plugging body, a connecting rod, a direction regulator and an outer plugging body, all of which are orderly arranged from the inner end to the outer end; the inner plugging body is provided with a mesh basket support and a first plugging film; the mesh basket support is formed by use of mesh basket wires and riveting hooks and protective balls are arranged on the mesh basket wires; the connecting rod is of a structure adjustable in length in the axial direction; the direction regulator is used for regulating the direction of the connecting rod; the outer plugging body is of a meshed hollow structure in a stand shape; the cross section of the outer plugging body is circular, while the longitudinal section of the outer plugging body is isosceles trapezoid-shaped; a second plugging film is arranged inside the outer plugging body; the first plugging film and the second plugging film both are microporous water-permeable films. According to the design ideal of inside plugging, the transcatheter left atrial appendage plugging system can be completely plugged without any residual cavity; the plugging system is suitable for the left atrial appendages different in shape and depth; besides, the plugging system is small in endothelialization area, steady in position after implantation and good in safety.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a transcatheter left atrial appendage occlusion system. Background technique [0002] Atrial fibrillation is a common heart rhythm disorder. The incidence of atrial fibrillation in adults is about 0.4%-2%. It is conservatively estimated that there are currently 8-10 million patients with atrial fibrillation in China. Patients with atrial fibrillation have a more than five-fold increased risk of stroke. Oral warfarin anticoagulation has been the cornerstone of anticoagulation therapy for AF. However, many defects and inconveniences in the application of warfarin greatly limit its clinical application. In my country, less than 10% of patients need long-term warfarin anticoagulant therapy according to the guidelines. Studies have confirmed that about 91% of thrombi in patients with atrial fibrillation originate from the left atrial appendage, so blocking the left atrial...

AI Technical Summary

Problems solved by technology

Almost all current occluders expose the rivets outside the atrial surface, which greatly delays the endothelialization time after device implantation

In addition, the "inner plug type" occluder has the following disadvantages: ①The design of the inner plug with a single structure is more suitable for the shape of the single-lobe left atrial appendage, and this type of left atrial appendage only accounts for a part; The catheter needs to go deep into the bottom of the left atrial appendage, and it is very easy to puncture the thin wall. Therefore, there are potential hidden dangers in the operation; ③The design of the inner plug type inevitably has a residual cavity, which may become a potential source of thrombus ;④It is not easy to control when the occluder is recovered, and the misplacement of small anchors often occurs, causing hidden dangers to subsequent successful operations

However, the "inner plug and outer cover" occluder still has several disadvantages: ①The design concept of a larger outer disc "covering" the opening of the left atrial appendage on the atrium surface requires that the diameter of the "lid" be larger than that of various left atrial appendage openings The largest diameter, so the larger "lid" may affect the surrounding structures, such as the mitral valve, left upper pulmonary vein, etc.; ②The larger outer disk is the larger endothelialization area, which will greatly delay the degree of endothelialization, becoming Potential source of device-related wall thrombus; ③Larger endothelialization area requires prolonging the use of warfarin and dual antiplatelet drugs, increasing the occurrence of adverse events such as bleeding and causing more medical expenses; ④Due to The left atrial appendage also has systolic and diastolic activities, and the "outer plugging" method, which is the method of surface bonding, has the problem of incomplete bonding.

[0005] In summary, the inventor believes that it is necessary to design an occluder that can be applied to various types of left atrial appendages, has a significant occlusion effect, a small endothelialized area, and better safety. No report

Images