Oral cavity anesthetic and preparation method thereof

An anesthetic and oral technology, which is applied in the field of traditional Chinese medicine compositions, can solve problems such as unsuitable swallowing and toad venom toxicity

Inactive Publication Date: 2015-09-30
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

From a pharmaceutical theory, toad venom should be the main drug in the above prescription, but toad venom has certain toxicity and should not be swallowed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] An oral anesthetic, in parts by weight, its specific component content is as follows:

[0018] 2 parts of raw Pinellia, 2 parts of pepper, 3 parts of Shenjincao, 2 parts of Asarum, 2 parts of Raw Nuxychonzi, 2 parts of Raw Grass Aconitum, 1 part of Piper Piper, 2 parts of Dandelion, 2 parts of Mint, 3 parts of LMZ 1 part, 3 parts of Liaoxiang, 1 part of Jiulixiang

[0019] The specific preparation method is as follows:

[0020] 1), weighing raw pinellia, pepper, shenjincao, asarum, raw nuxychonna, raw grass aconitum, Piperia, dandelion, peppermint, double-faced needle, liaoxiang, and jiulixiang according to the weight parts; 2) Add 10 to 20 times the weight of water to extract twice, the first extraction for 1 to 2 hours, the second for 0.5 to 1.5 hours, combine the extracts, filter, centrifuge, let stand, take the supernatant, and concentrate under reduced pressure to obtain The relative density is 1.19-1.50 clear ointment; 3) adding alcohol into the clear ointment a...

Embodiment 2

[0022] An oral anesthetic, in parts by weight, its specific component content is as follows:

[0023] 8 parts of Raw Pinellia, 8 parts of Pepper, 5 parts of Shenjincao, 5 parts of Asarum, 10 parts of Raw Nuxychia, 8 parts of Raw Grass Aconitum, 3 parts of Piper Piper, 8 parts of Dandelion, 8 parts of Mint, and 5 parts of Two-faced Acupuncture 5 parts of Liaoxiang, 5 parts of Jiulixiang

[0024] Concrete preparation method is with embodiment 1.

Embodiment 3

[0026] An oral anesthetic, in parts by weight, its specific component content is as follows:

[0027] 6 parts of raw Pinellia, 6 parts of pepper, 4 parts of Shenjincao, 4 parts of Asarum, 5 parts of raw Nuxychia, 6 parts of Raw Grass Aconitum, 2 parts of Piper Piper, 6 parts of Dandelion, 6 parts of Mint, 4 parts of Two-faced Acupuncture 4 parts of Liaoxiang, 3 parts of Jiulixiang

[0028] Concrete preparation method is with embodiment 1.

[0029] Clinical data:

[0030] The loose teeth to be extracted were all degree II and III loose. Among the 624 cases aged 7-80, there were 228 cases of deciduous anterior teeth, 159 cases of deciduous molars, 180 cases of permanent anterior teeth, and 95 cases of permanent molars. Use the traditional Chinese medicine anesthetic of the present invention, prepare before routine tooth extraction, gargle with boric acid water, local disinfection, dry the anesthetized local area, dip a rod-shaped cotton tampon into the anesthetic of the prese...

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PUM

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Abstract

The invention relates to oral cavity anesthetic. The oral cavity anesthetic comprises raw pinellia ternate, pepper, lycopodium clavatum, asarum herbs, raw semen strychni, wild aconite roots, long pepper, dandelions, mint, shinyleaf pricklyash roots, musk and kamuning. The oral cavity anesthetic and a preparation method thereof aim at the understanding of the mechanism of body surface anesthesia by traditional Chinese medicine, particular to the fact that oral cavity anesthesia has high requirements on medicine safety, all medicine components of the anesthetic are in scientific compatibility, and the main mechanism is that through the permeation of the medicine, nerve endings are anesthetized, the anesthesia effect is good, the pain killing effect is achieved, and meanwhile the anti-inflammation and anti-swelling effects are achieved. No toxic or side effect exists, and the oral cavity anesthetic does not contain arenobufagin.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, a body surface anesthetic, especially an oral anesthetic and a preparation method thereof. Background technique [0002] Traditional Chinese medicine superficial anesthesia prescriptions have been used at the latest in the Tang Dynasty, but they have not been well inherited and developed in the following hundreds of years. It was not until the late Ming and early Qing Dynasties that anesthesia for external use of traditional Chinese medicine developed by leaps and bounds, and played an important role in the treatment of certain diseases requiring surgery in traditional Chinese medicine surgery, traumatology and laryngology. [0003] Oral anesthetics are one of the surface anesthetics. Because they are used in the oral cavity, the composition of the drug is more cautious than that of ordinary surface anesthetics. Ma Lili et al. used a compound traditional Chinese medicine anesthetic a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8888A61P23/02A61P1/02
Inventor 刘玉秋王野卢菁王梓
Owner QINGDAO MUNICIPAL HOSPITAL
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