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Temperature-responsive hydrogel and preparation method thereof

A temperature-responsive, hydrogel technology, applied in the field of hydrogel, can solve the problem that the double-network hydrogel does not have temperature, etc., and achieve the effect of good temperature response characteristics, good mechanical properties, and large volume deformation

Inactive Publication Date: 2015-10-07
ZHEJIANG UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the double-network hydrogels prepared by it do not have temperature-responsive properties.

Method used

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  • Temperature-responsive hydrogel and preparation method thereof
  • Temperature-responsive hydrogel and preparation method thereof
  • Temperature-responsive hydrogel and preparation method thereof

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Embodiment Construction

[0033] The present invention will be described in detail below with reference to the drawings and specific embodiments.

[0034] The temperature-responsive hydrogel of this embodiment includes cross-linked first network monomers and second network monomers. The network structure formed by the first network monomers is a flexible network and has temperature responsive properties. The second network monomers The network structure formed by the body is a rigid network. The mass percentage of water in the hydrogel of this embodiment is 80%.

[0035] In this embodiment, the first network monomer is N-isopropylacrylamide, and the second network monomer is sodium alginate.

[0036] The temperature-responsive hydrogel of this example was prepared by the following method:

[0037] (1) Dissolve N-isopropylacrylamide, sodium alginate, N-isopropylacrylamide cross-linking agent N,N'-methylenebisacrylamide and photoinitiator ammonium persulfate into the mixed solution , wherein the mass ...

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Abstract

The invention discloses temperature-responsive hydrogel and a preparation method thereof. The temperature-responsive hydrogel comprises a first network monomer and a second network monomer crosslinked with the first network monomer. The first network monomer forms a flexible network structure and has temperature responsiveness. The second network monomer has a rigid network structure. The temperature-responsive hydrogel has good temperature responsiveness, can produce large volume deformation by change of an extraneous environment, has good mechanical properties, can bear a large outside force, can form 4-5 time deformation under action of an outside force and has modulus of about 30KPa.

Description

technical field [0001] The invention relates to the field of hydrogel technology, in particular to a temperature-responsive hydrogel and a preparation method thereof. Background technique [0002] Hydrogel material is a kind of soft material formed by filling water molecules in polymer network structure. Because of its wet and soft properties, it is widely used in bioengineering, drug delivery, tissue engineering and other fields. Smart hydrogel material is a kind of hydrogel, which is very sensitive to changes in the external environment. If there are small changes in external temperature, pH, photoelectric signal, special chemical molecules and other factors, the smart hydrogel itself will be able to respond accordingly. A change in physical or chemical structure. Therefore, since smart hydrogels can quickly indicate changes in certain external environmental factors, change their volume or respond in other properties under certain external stimuli, some smart hydrogels w...

Claims

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Application Information

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IPC IPC(8): C08F251/00C08F220/54C08F2/48
Inventor 李铁风杨栩旭李驰谢雨涵梁艺鸣
Owner ZHEJIANG UNIV
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