A traditional Chinese medicine compound composition for treating chronic atrophic gastritis and precancerous lesions and its preparation method and preparation

Abstract

The invention relates to the pharmaceutical field, and in particular discloses a traditional Chinese medicinal compound composition and preparation for treating chronic atrophic gastritis and precancerous lesion as well as a preparation method of the traditional Chinese medicinal compound composition. The traditional Chinese medicinal compound composition for treating chronic atrophic gastritis and precancerous lesion consists of the following components: fried rhizoma atractylodis macrocephalae, ganoderma lucidum, curcuma zedoary, parched white peony root, calcined ocher, diverse wormwood herb and oldenlandia diffusa. The traditional Chinese medicinal compound composition disclosed by the invention has the effects of improving clinical symptoms in patients, relieving or eliminating mucosa inflammation and activity under gastroscope, and interrupting and reversing partial atrophy, mild and moderate intestinal metaplasia as well as mild dysplasia. In accordance with regulations, the composition is applicable to patients of chronic atrophic gastritis and precancerous lesion with the following clinical symptoms: discomfort in gastric cavity, pain or distension, repeated disunion, or discomfort in mouth, dry or loose stool, poor sleep, depression or dysphoria, thin yellow or thin clean tongue fur, cracks in tongue fur, dark purple sublingual venation, and thready and slippery pulse.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a traditional Chinese medicine compound composition for treating chronic atrophic gastritis and precancerous lesions, a preparation method and a preparation thereof. Background technique [0002] Chronic atrophic gastritis (CAG) is a digestive system disease characterized by atrophy of gastric mucosal glands and intestinal metaplasia. Gastric cancer lesions include: atrophy, intestinal metaplasia, dysplasia, etc. Gastric mucosal carcinogenesis is a multi-step, gradual process, often undergoing years of continuous precancerous changes before developing into a malignant tumor. China is an area with a high incidence of chronic atrophic gastritis. The detection rate of gastroscopy in the population ranges from 7.5% to 13.8%. Gastric cancer occurs in nearly 8% of cases after 10 to 20 years of follow-up. Therefore, the implementation of chronic atrophic gastritis and precancerous lesions of ...

AI Technical Summary

Problems solved by technology

The main drugs that have been confirmed so far are: folic acid can reduce the risk of gastric cancer; natural carotene can reverse dysplasia; tea polyphenols can induce apoptosis of human gastric cancer cells; others such as cyclooxygenase-2 inhibitors, anti- Oxidants are promising reversal methods, but further research and clinical verification are still needed

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