Planning the irradiation of a particle beam while taking into consideration a movement of a target volume
A technology of target volume and movement, applied in X-ray/γ-ray/particle irradiation therapy, radiotherapy, treatment, etc., to save time, improve uniformity, and improve uniformity
Active Publication Date: 2015-10-14
GSI重离子研究亥姆霍茨中心有限公司
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However, healthy tissue may thus have to be irradiated in order to ensure a reliable dose range in the target volume
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[0042] figure 1 A schematic configuration of a particle therapy installation 10 known per se is shown. The particle therapy facility 10 generates and accelerates loaded particles which are provided for further use in the form of a particle beam 20 and which are steerable by means of a beam guiding device 17 into a definable target volume 34 (cf. image 3 )middle. The target volume 34 contains tumors, for example in the context of tumor therapy, but for scientific purposes, animal experiments, models and material samples and generally for research particle beams and / or particle therapy can also define objects containing inanimate materials and / or cell cultures Volume 34. The particle therapy installation 10 is also used to irradiate a simulator with the particle beam 20 , by means of which a number of irradiation parameters can be checked before and / or after irradiation or treatment of a patient.
[0043] particles in figure 1 In the example shown, generation and pre-accele...
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The invention relates to a method for planning the irradiation of a moving target volume arranged in a body by means of a rescanning process using a particle irradiation system. The method has the steps of determining the target volume in a reference state of the movement, dividing the target volume into a plurality of target points which can be individually struck with a particle beam, calculating a target dose to be deposited at each of the target points of the target volume, determining a number of rescan passes in which each of the target points of the target volume is struck, calculating an expected average movement of the target points of the target volume using a movement model, taking into consideration the expected average movement of the target points of the target volume while planning the irradiation such that the deviation of the expected dose deposit from the target dose is detected for each target point and the target dose is corrected for each target point on the basis of the deviation, and generating control parameters for the irradiation system, said control parameters comprising a particle number to be applied per target point and rescan pass.
Description
technical field [0001] The invention relates to methods and devices for irradiation planning and accelerator installations with particle beams. Background technique [0002] Tumor therapy using heavy ions has developed over the last few decades as an established method for treating tissues, especially tumor diseases. However, the experience gained here can also be used in purely technical fields, such as, for example, within the scope of research work or product development, in which inanimate materials are used. [0003] A common feature of all known methods here is that the concentrated particle beam provided by the accelerator system is guided into one or more irradiation or treatment chambers by means of a high-energy beam delivery system. A target volume to be irradiated is positioned in the irradiation chamber and irradiated with the particle beam. [0004] It is known that the target volume to be irradiated can be moved. For example, a lung tumor can be provided in...
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IPC IPC(8): A61N5/10
CPCA61N5/1037A61N5/1049A61N2005/1072A61N5/1044A61N5/1031A61N5/1065
Inventor C·贝尔特A·吉梅尔D·米西希R·卢赫滕贝格
Owner GSI重离子研究亥姆霍茨中心有限公司