Compound Flunixin meglumine injection and preparation method thereof

A technology for flunixin meglumine and injection, which is applied in the field of compound flunixin meglumine injection and its preparation, can solve the problems of bacterial drug resistance, difficult disease treatment, and drug endangering human health, etc. Reliable curative effect, improve and disease resistance, improve the effect of immunity

Inactive Publication Date: 2015-12-02
河南亚卫动物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented new chemical entity called Compensate Microcathopines was found earlier than previously believed effective against various types of microorganisms like salmonelloids or enterotoxigenes without causing damage to their tissues. These molecules have been shown to kill both Gram negative and positive bacteriae effectively while being less likely to cause side reactions with these organism. They may even enhance the ability of some medicaments to fight off intestinal illnesses when given through traditional methods.

Problems solved by technology

This patented technical problem addressed by this patents relates to developing safer and less expensive ways to administer vaccine or medicine into animals without causing harmful reactions from them due to their resistant properties.

Method used

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  • Compound Flunixin meglumine injection and preparation method thereof
  • Compound Flunixin meglumine injection and preparation method thereof

Examples

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Effect test

Embodiment 1

[0017] A compound flunixin meglumine injection containing the following components by weight percentage: 8.6% flunixin meglumine, 3% honeysuckle extract, 5% baicalin, 5% taurine, and 5% cecropin , Polyoxyethylene 40 hydrogenated castor oil 12%, propylene glycol 20.8%, ethanol 8%, Tween 800.5%.

[0018] The preparation method of the compound flunixin meglumine injection comprises the following steps: (1) Weigh an appropriate amount of water for injection and heat it to 50°C, add baicalin, adjust the pH value to 7.0, and dissolve all the baicalin;

[0019] (2) Weigh an appropriate amount of water for injection and heat it to 60°C, add Tween 80, stir evenly, then add polyoxyethylene 40 hydrogenated castor oil, taurine, and cecropin in sequence, and stir to dissolve;

[0020] (3) Heat propylene glycol to 55°C, add flunixin meglumine and honeysuckle extract in turn, stir to dissolve; then add the solutions in step (1) and step (2), and then add 95% ethanol (volume fraction) , afte...

Embodiment 2

[0022] A compound flunixin meglumine injection containing the following components by weight percentage: 8% flunixin meglumine, 5% honeysuckle extract, 1% baicalin, 3% taurine, 1% cecropin , Polyoxyethylene 40 hydrogenated castor oil 10%, propylene glycol 10%, ethanol 1%, Tween 801%.

[0023] The preparation method of the compound flunixin meglumine injection comprises the following steps: (1) Weigh an appropriate amount of water for injection and heat it to 60°C, add baicalin, adjust the pH value to 7.6, and dissolve all the baicalin;

[0024] (2) Weigh an appropriate amount of water for injection and heat to 50°C, add Tween 80, stir evenly, then add polyoxyethylene 40 hydrogenated castor oil, taurine, and cecropin in sequence, and stir to dissolve;

[0025] (3) Heat propylene glycol to 60°C, add flunixin meglumine and honeysuckle extract in turn, stir to dissolve; then add the solutions in step (1) and step (2), then add absolute ethanol, stir well , adjust the pH value to ...

Embodiment 3

[0027] A compound flunixin meglumine injection, which contains the following components by weight percentage: 10% flunixin meglumine, 1% honeysuckle extract, 3% baicalin, 10% taurine, and 10% cecropin , Polyoxyethylene 40 hydrogenated castor oil 15%, propylene glycol 15%, ethanol 20%, Tween 800.8%.

[0028] The preparation method of the compound flunixin meglumine injection comprises the following steps: (1) Weigh an appropriate amount of water for injection and heat it to 55°C, add baicalin, adjust the pH value to 7.3, and dissolve all the baicalin;

[0029] (2) Weigh an appropriate amount of water for injection and heat it to 55°C, add Tween 80, stir well, then add polyoxyethylene 40 hydrogenated castor oil, taurine, cecropin in turn, stir to dissolve;

[0030] (3) Heat propylene glycol to 50°C, add flunixin meglumine and honeysuckle extract in turn, stir to dissolve; then add the solutions in step (1) and step (2), then add absolute ethanol, stir well , adjust the pH value...

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Abstract

The invention belongs to compound Flunixin meglumine injection and a preparation method thereof. The compound Flunixin meglumine injection comprises, by weight percentage, 8-10% of Flunixin meglumine, 1-5% of honeysuckle extract, 1-5% of baicalin, 3-10% of taurine, 1-10% of cecropin, 10-15% of polyoxyethylene 40 hydrogenated castor oil, 10-21% of propylene glycol, 1-20% of ethanol and 0.5-1% of tween 80. The compound Flunixin meglumine injection has the advantages that the compound Flunixin meglumine injection combines Chinese and western medicine, has antipyretic and analgesic effects and antibacterial and anti-inflammation effects, and is capable of increasing organism immunity and disease resistance and evidently changing clinical symptoms; the compound Flunixin meglumine injection is long in curative effect duration, the cost is lowered, stress reactions, caused by multiple injection, of animals are reduced, bacterium drug resistance cannot be generated easily, and the compound Flunixin meglumine injection is low in toxicity, reliable in curative effect and lasting in effect.

Description

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Claims

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Application Information

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Owner 河南亚卫动物药业有限公司
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