Oral solution for treating radioactive xerostomia

A xerostomia and radioactive technology, applied in the field of traditional Chinese medicine, can solve problems such as weakened secretory function, poor curative effect, oral mucositis, and dysphagia

Inactive Publication Date: 2016-02-24
钟柱林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For now, radiotherapy often cannot avoid damage to the oral cavity, leading to salivary gland atrophy, weakened or lost secretory function, which in turn leads to unbearable dry mouth, oral mucositis, and dysphagia after radiotherapy, seriously affecting the patient's health. Quality of Life
[0003] At present, the treatment of xerostomia after radiotherapy usually uses hormones and acidic drugs or food to stimulate salivary gland secretion, but the efficacy is not good, and there is no effective way to directly combat this side effect of radiotherapy

Method used

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  • Oral solution for treating radioactive xerostomia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] The preparation of embodiment 1 Chinese medicine oral liquid

[0015] Herbal medicine prescription: Codonopsis 2.6kg, Betel nut flower 0.8kg, Campanulaceae 1.5kg, Artemisia annua 1.5kg, Bupleurum 0.8kg, sea octopus 0.8kg, Euphorbia villosa 1.2kg, Angelica dahurica 0.8kg.

[0016] Preparation process: Weigh the above-mentioned Chinese herbal medicines in the prescribed amount, mix them evenly in a sandwich pot, add 12 times the total amount of medicinal materials in water, soak for 10 minutes, heat and boil for 1 hour, filter after cooling, and add 10 times the total amount of medicinal materials to the filter residue in water Heat and boil for 1 hour, then filter, and combine the two filtrates; then add 70% ethanol to the filter residue until it covers 1 cm of the drug surface, soak for 3 hours, press and filter, and combine with the above filtrate to obtain a mixed filtrate; then heat the mixed filtrate to reflux until alcohol-free taste, concentrated until 1ml of liqu...

Embodiment 2

[0017] The preparation of embodiment 2 Chinese medicine oral liquid

[0018] Herbal medicine prescription: Codonopsis 2.2kg, betel nut flower 1.0kg, bellflower 1.6kg, artemisia annua 1.6kg, Bupleurum 1.0kg, sea octopus 0.8kg, long hair 1.3kg, angelica dahurica 1.0kg.

[0019] Preparation process: Weigh the above-mentioned Chinese herbal medicines in the prescribed amount, mix them evenly in a sandwich pot, add 12 times the total amount of medicinal materials in water, soak for 10 minutes, heat and boil for 1 hour, filter after cooling, and add 10 times the total amount of medicinal materials to the filter residue in water Heat and boil for 1 hour, then filter, and combine the two filtrates; then add 70% ethanol to the filter residue until it covers 1 cm of the drug surface, soak for 3 hours, press and filter, and combine with the above filtrate to obtain a mixed filtrate; then heat the mixed filtrate to reflux until alcohol-free taste, concentrated until 1ml of liquid medicine...

Embodiment 3

[0020] The preparation of embodiment 3 Chinese medicine oral liquid

[0021] Prescription of herbal medicine: Codonopsis 2.8kg, Betel nut flower 1.0kg, Campanulaceae 1.4kg, Artemisia annua 1.8kg, Bupleurum 0.9kg, sea octopus 0.9kg, Euphorbia villosa 1.5kg, Angelica dahurica 1.0kg.

[0022] Preparation process: Weigh the above-mentioned Chinese medicinal materials in the prescribed amount, mix them evenly in a sandwich pot, add water to cover the medicine surface 2cm, soak for 10 minutes, heat and boil for 1 hour, filter after cooling, add appropriate amount of water to the filter residue, heat and boil for 1 hour, and then filter , combine the two filtrates; then add 70% ethanol to the filter residue until it covers 1cm of the medicinal surface, soak for 3h, squeeze and filter, and combine with the above filtrate to obtain a mixed filtrate; then heat the mixed filtrate to reflux until it has no alcohol smell, and concentrate to 1ml medicinal Contain 1g of the original drug in ...

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Abstract

The invention relates to an oral solution for treating radioactive xerostomia. The oral solution for treating the radioactive xerostomia is prepared from, by weight, 22-30 parts of codonopsis pilosula, 6-10 parts of betelnutpalm male flower, 11-18 parts of platycodon grandiflorum, 11-18 parts of a sweet wormwood herb, 6-10 parts of radix bupleuri, 6-10 parts of cuttlebone, 9-15 parts of eurya patentipila chun and 6-10 parts of angelica dahurica. The oral solution for treating the radioactive xerostomia can relieve the mouth dryness symptom arisen after radiotherapy, keep the mouth moist and clean and increase appetite and also can reduce discomfort caused by treatment.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to an oral liquid for treating xerostomia caused by radiotherapy of nasopharyngeal carcinoma. Background technique [0002] More than 90% of nasopharyngeal carcinoma is poorly differentiated squamous cell carcinoma, which is more sensitive to radiation. The primary tumor and cervical metastases can be included in the irradiation range at the same time. Radiation therapy is currently the preferred treatment for nasopharyngeal carcinoma. While radiation therapy kills tumors, it also causes great damage to normal tissues and organs in the radiation field, which leads to the emergence of radiation therapy complications. Dry mouth and throat after radiotherapy is one of the serious complications after radiotherapy for nasopharyngeal carcinoma. Due to radiotherapy, salivary glands are damaged or lost function, which seriously affects the quality of life of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K9/08A61P1/02A61K35/618
Inventor 钟柱林
Owner 钟柱林
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