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Propionic acid polyhexamethylene guanidine oral spray

A technology of polyhexamethyleneguanidine propionate and oral spray, which is applied in the direction of anti-inflammatory agent, aerosol delivery, non-central analgesic, etc., can solve the problem of long-term use effect reduction, and achieve unabated, Use safe and reliable, the effect is obvious

Inactive Publication Date: 2016-03-02
卫国刚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Existing oral sprays can irritate mucous membranes, skin, and wounds, have certain drug resistance, and will reduce the effect of long-term use

Method used

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  • Propionic acid polyhexamethylene guanidine oral spray
  • Propionic acid polyhexamethylene guanidine oral spray
  • Propionic acid polyhexamethylene guanidine oral spray

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Embodiment Construction

[0013] The present invention will be further described below in conjunction with specific embodiments.

[0014] In order to make the objectives, technical solutions and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with specific embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention, and not to limit the present invention.

[0015] This specific embodiment adopts the following technical scheme: Its formula is as follows:

[0016]

[0017]

[0018] The production process is as follows:

[0019] 1. Prepare 0.05% mint and 0.05% solubilizer and stir for 15-20 minutes to obtain water-soluble mint solution A;

[0020] 2. Add 0.5% polyhexamethylene guanidine propionate and 1% synergist to 77.9% purified water in sequence, and stir for 5-10 minutes to obtain solution B;

[0021] 3. After stirring uniformly, add water-soluble mint solution A, 2...

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Abstract

The invention discloses a propionic acid polyhexamethylene guanidine oral spray and relates to the field of oral sprays. According to the formula, the oil spray is prepared from the following raw materials of 0.05%-0.5% of propionic acid polyhexamethylene guanidine, 1% of synergist, 20%-30% of glycerinum, 0.001%-0.5% of saccharin sodium, 0.05% of mint, 0.05% of solubilizer and 67.9%-79% of purified water. The production process comprises the following steps that the mint and the solubilizer are prepared according to the proportion and stirred for 15-20 minutes, and a water soluble mint solution A is obtained; the propionic acid polyhexamethylene guanidine and the synergist are added to the purified water sequentially according to the proportion and stirred for 5-10 minutes, and a solution B is obtained; the water soluble mint solution A, the glycerinum and the saccharin sodium are added to the solution B sequentially according to the proportion after the solution B is stirred uniformly, stirring is performed for 20-30 minutes, and the propionic acid polyhexamethylene guanidine oral spray is obtained. The propionic acid polyhexamethylene guanidine oral spray has the advantages that the oral spray is rapid to take effect, has no stimulation to mucosa, skin and the wound, no toxic or side effect or drug resistance, and has high cover protection capacity and the function of repairing and improving mucosa defense.

Description

Technical field: [0001] The invention relates to the field of oral sprays, in particular to a polyhexamethylene guanidine propionate oral spray. Background technique: [0002] Oral spray, heat-clearing and detoxifying, anti-inflammatory and analgesic, used to treat stomatitis, oral ulcers, pharyngitis, etc. [0003] The existing oral sprays will cause certain irritation to mucous membranes, skin, and wounds, have certain drug resistance, and will reduce their long-term use effect. Summary of the invention: [0004] The purpose of the present invention is to provide a rationally designed oral spray of polyhexamethylene guanidine propionate in view of the defects and deficiencies of the prior art. It has fast onset, rapid sterilization, and obvious effects, and has no effect on mucous membranes, skin, and wounds. Stimulating, non-toxic side effects, safe and reliable to use, unique germicidal principle makes it non-drug resistant, long-term use effect is not diminished, and has stron...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/12A61K31/785A61P1/02A61P11/04A61P7/04A61P29/00
CPCA61K9/006A61K9/12A61K31/785
Inventor 卫国刚
Owner 卫国刚
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