A quality detection method for traditional Chinese medicine prescriptions

Abstract

The invention discloses a quality detection method of a traditional Chinese medicine prescription, and the existing name of the traditional Chinese medicine prescription is Compound Baidu Decoction. The method for detecting the quality of traditional Chinese medicine prescriptions in the present invention is to simultaneously measure the contents of astilbin, forsythiaside A and forsythin in Compound Baidu Decoction by using ultra-high-speed liquid chromatography (UPLC) at 275 nm. The method of the present invention adopts UPLC to measure each effective medicinal component of Compound Baidu Decoction, and has ultra-high separation, ultra-high speed, and ultra-high sensitivity for the components such as astilbin, forsythiaside A, and forsythin. and other advantages; better chromatographic peak resolution can be obtained in one sample injection, without complicated sample pretreatment process, greatly improving the chromatographic resolution and analysis speed, effectively saving analysis time, and realizing rapid and high-resolution compound extraction The quality analysis of Dutang traditional Chinese medicine has a good effect on clinical quality control.

Description

technical field [0001] The invention relates to a prescription of traditional Chinese medicine, in particular to a method for detecting and analyzing the quality of a prescription of traditional Chinese medicine. Background technique [0002] The traditional Chinese medicine prescription involved in the present invention is the agreement prescription of the 302nd Hospital of the People's Liberation Army. Rhodiola 5 ~ 20g composition, wherein Astragalus is the dry root of the perennial herb Astragalus mongolica or Astragalus membranaceus; Smilax is the dry rhizome of perennial climbing vine Smilax glabra in Liliaceae; The dried whole grass of the annual grassland ear grass; Forsythia is the dry fruit of the deciduous shrub Forsythia oleifera; Rhodiola is the dried rhizome of the perennial herb Rhodiola or Rhodiola latifolia in the family Sedum. The main medicinal ingredients are Forsythia, Smilax, etc., which have the effects of strengthening the spleen and kidney, soothing ...

AI Technical Summary

Problems solved by technology

[0003] However, for Compound Baidu Decoction, if the commonly used HPLC technology is used, it is found that the chromatographic peaks of the complex components in the compound cannot be separated at all. Satisfactory chromatographic peak resolution cannot be obtained, so it is necessary to find other suitable analytical methods to achieve the technical purpose of simultaneously determining the main medicinal components in Compound Baidu Decoction, and to achieve rapid, high-speed, and high-sensitivity determination And the technical effect of the determination method is simple and easy

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