Method for relieving neurosurgery postoperative agitation under sevoflurane general anesthesia condition

Abstract

The invention discloses a method for relieving neurosurgery postoperative agitation under a sevoflurane general anesthesia condition. The method comprises steps as follows: intramuscular injection of 0.06 mg*kg<-1> of midazolam and 0.3 mg of scopolamine is performed on a patient 30 min before an operation, and the venous access is open after entrance; anesthesia induction: intravenous injection of 0.03 mg*kg<-1> of etomidate, 5 mu g*kg<-1> of fentanyl and 1 mg*kg<-1> of atracurium is performed on the patient; anesthesia maintenance: 3%-5% of sevoflurane is inhaled, the oxygen flow is 1.5 L / min, the concentration of sevoflurane is monitored by an anesthesia gas monitor, the MAC (minimum alveolar concentration) value is controlled within 1.3-1.5, continuous intravenous infusion of 2 mg*kg-1*h<-1> of propofol is performed, the blood pressure is controlled to be 20%-25% of the basic blood pressure, and discontinuous intravenous injection of atracurium is performed for maintaining muscular relaxation. During the operation, a Datex ECG monitor is adopted to perform routine monitoring of respiration and circulation functions, arterial blood gas analysis and electrolyte check are performed, and the homeostasis is maintained. Inhalation of sevoflurane is stopped 10 min before the operation is ended, and phlegm suction extubation is performed when autonomous respiration tidal volume is larger than 8 ml*kg-1, the blood oxygen saturation is larger than 95% and swallowing reflex recovers.

Description

technical field [0001] The invention relates to a method for alleviating restlessness after neurosurgery under general anesthesia with sevoflurane, in particular to a method for alleviating restlessness after neurosurgery under general anesthesia with sevoflurane. Background technique [0002] The currently known sevoflurane has the advantages of small blood / air partition coefficient, low liver toxicity, slight impact on breathing, circulation, intracranial pressure, etc., and rapid recovery, which is conducive to timely observation of the condition after surgery, and is suitable for neurosurgery. anaesthetization. However, the study found that patients with sevoflurane inhalation general anesthesia had a higher incidence of postoperative agitation, and the longer the sevoflurane inhalation time, the higher the incidence of postoperative agitation. Postoperative agitation affects the prognosis of patients. Patients with agitation often have higher sympathetic nervous system...

AI Technical Summary

Problems solved by technology

Flurbiprofen axetil lipid microsphere injection (trade name: Kaifen) is a new dosage form of non-steroidal anti-inflammatory analgesics for intravenous injection of lipid microspheres. Can it safely relieve postoperative restlessness after neurosurgery? There are literature reports