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Drug combination for treating esophagus cancer and preparation method thereof

A composition and technology for esophageal cancer, which are applied in the directions of drug combinations, pharmaceutical formulations, active ingredients of heterocyclic compounds, etc., can solve the problems of unclear pathogenesis of esophageal cancer, uncertainty of treatment methods, etc.

Inactive Publication Date: 2016-06-15
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, the pathogenesis of esophageal cancer is not clear, and its treatment method also has great uncertainty, so it is still necessary to deeply study the etiology and clinical treatment of esophageal cancer.

Method used

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  • Drug combination for treating esophagus cancer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Example 1: Pharmaceutical composition for treating esophageal cancer and its preparation method

[0038] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating esophageal cancer are: 245g asarin, 365g cotton ginseng, 4700g cichoroside, 186g violaline, 150g, 125g crotonepoxy;

[0039] Preparation:

[0040] (1) According to the ratio of raw materials, take asarin, echinacea, cotton ginseng, chicoryin, corydalin, crotonepoxy, mix well, use ethanol with a concentration of 33.5% by weight as a solvent, and mix it at 32 ℃ warm immersion extraction, the number of extractions is 15 times, each extraction time is 10 hours, and the amount of solvent used each time is 26 times the total weight of the raw material drug, and filtered to obtain medicinal residue A and extract A, and the extract A reclaims ethanol, Concentrate to a relative density of 1.20, filter, the drug solution passes through the CAD-45 macroporous adsorption resin c...

Embodiment 2

[0043] Example 2: Pharmaceutical composition for treating esophageal cancer and its preparation method

[0044] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating esophageal cancer are: asarin 230g Echinacea 380g cotton ginseng 4600g cichoroside 188g violaline 140g crotonepoxy 130g;

[0045] Preparation:

[0046] (1) According to the ratio of raw materials, take asarin, echinacea, cotton ginseng, chicoryin, corydalin, crotonepoxy, mix well, use ethanol with a concentration of 33.5% by weight as a solvent, and mix it at 32 ℃ warm immersion extraction, the number of extractions is 15 times, each extraction time is 10 hours, and the amount of solvent used each time is 26 times the total weight of the raw material drug, and filtered to obtain medicinal residue A and extract A, and the extract A reclaims ethanol, Concentrate to a relative density of 1.20, filter, the drug solution passes through the CAD-45 macroporous adsorp...

Embodiment 3

[0049] Example 3: Pharmaceutical composition for treating esophageal cancer and its preparation method

[0050] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating esophageal cancer are: 260g asarin, 350g cotton ginseng, 4800g cichoroside, 180g violaline, 160g, 120g crotonepoxy;

[0051] Preparation:

[0052] (1) According to the ratio of raw materials, take asarin, echinacea, cotton ginseng, chicoryin, corydalin, crotonepoxy, mix well, use ethanol with a concentration of 33.5% by weight as a solvent, and mix it at 32 ℃ warm immersion extraction, the number of extractions is 15 times, each extraction time is 10 hours, and the amount of solvent used each time is 26 times the total weight of the raw material drug, and filtered to obtain medicinal residue A and extract A, and the extract A reclaims ethanol, Concentrate to a relative density of 1.20, filter, the drug solution passes through the CAD-45 macroporous adsorption resin c...

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Abstract

The invention discloses a pharmaceutical composition for treating esophageal cancer and a preparation method thereof. The pharmaceutical composition of the invention is composed of asarin, echinacea, cotton ginseng, chicoryin, corydalin, crotonepoxy It is a raw material medicine prepared in proportion, and can be made into various dosage forms according to conventional preparation techniques, and has remarkable curative effect in treating esophagus cancer.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating esophageal cancer and a preparation method thereof. Background technique [0002] With the continuous development of epidemiological research on esophageal cancer in recent years, the research progress of esophageal cancer is gradually deepening. At present, it is generally believed that the causes of esophageal cancer are diversified, and many factors may lead to the occurrence of esophageal cancer. Excessive intake of People with mold, people with hereditary family, people addicted to tobacco and alcohol, and people who ingest a lot of nitrosamines are all prone to esophageal cancer. Paying attention to eating habits in life and avoiding foods containing nitrosamines can help prevent esophageal cancer happened. For the treatment of esophageal cancer, although the effect of Western medicine is quicker, ...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61P35/00A61K31/4355A61K31/36A61K31/7048A61K31/336
CPCA61K36/28A61K9/1652A61K9/2031A61K9/2059A61K31/336A61K31/36A61K31/4355A61K31/7048A61K36/53A61K2236/333A61K2236/39A61K2236/55
Inventor 不公告发明人
Owner JINAN XINGYI MEDICAL TECH
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