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Pharmaceutical composition for thyroid cancer postoperative recurrent thyroid nodule

A technology for thyroid nodules and thyroid cancer, which is applied in the field of traditional Chinese medicine to achieve the effects of avoiding inconvenience in taking, less adverse reactions, and clear compatibility relationship

Inactive Publication Date: 2016-09-07
QINGDAO YUNTIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, Western medicine treatment shows certain limitations

Method used

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  • Pharmaceutical composition for thyroid cancer postoperative recurrent thyroid nodule
  • Pharmaceutical composition for thyroid cancer postoperative recurrent thyroid nodule
  • Pharmaceutical composition for thyroid cancer postoperative recurrent thyroid nodule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1 capsule

[0037] Prescription: 8 parts of kumquat leaves, 18 parts of jasmine flowers, 12 parts of jasmine vine, 15 parts of Xiaoxue ginseng, 12 parts of medlar leaves, 15 parts of chinensis, 13 parts of bitter grass, 6 parts of calcined corrugated seeds, 10 parts of peony bark, 17 parts of Shichancao.

[0038] Preparation method: take kumquat leaves, jasmine flowers, jasmine vines, snow ginseng, medlar leaves, chinensis, big licorice, peony bark, and cicada grass according to the prescription, and grind them into coarse powder, add 6 times the weight of water to soak 3- 4 hours, decoct for 1-2 hours, filter and collect the filtrate, add water to the filter residue to be 5 times the weight of the medicinal material, decoct for 1-1.5 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.08 (measured at 60°C). ), add ethanol to make the alcohol content reach 45%, let it stand for 12 hours, filter...

Embodiment 2

[0039] Embodiment 2 capsules

[0040] Prescription: 10 parts of kumquat leaves, 15 parts of jasmine flowers, 15 parts of jasmine vine, 15 parts of Xiaoxue ginseng, 10 parts of medlar leaves, 12 parts of chinensis, 15 parts of big licorice, 6 parts of calcined corrugated seeds, 12 parts of peony bark, 15 parts of Shichancao.

[0041] Preparation method: take kumquat leaves, jasmine flowers, jasmine vines, snow ginseng, medlar leaves, chinensis, big licorice, peony bark, and cicada grass according to the prescription, and grind them into coarse powder, add 6 times the weight of water to soak 3- 4 hours, decoct for 1-2 hours, filter and collect the filtrate, add water to the filter residue to 4 times the weight of the medicinal material, decoct for 1-1.5 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.10 (measured at 60°C) ), add ethanol to make the alcohol content reach 45%, let it stand for 12 hours, filter, ...

Embodiment 3

[0042] Embodiment 3 capsules

[0043] Prescription: 12 parts of kumquat leaves, 20 parts of jasmine flowers, 10 parts of jasmine vine, 17 parts of Xiaoxue ginseng, 15 parts of medlar leaves, 10 parts of chinensis, 15 parts of licorice, 5 parts of calcined corrugated seeds, 8 parts of peony bark, 20 parts of Shichancao.

[0044] Preparation method: take kumquat leaves, jasmine flowers, jasmine vines, snow ginseng, medlar leaves, chinensis, big bitter grass, peony bark, and cicada grass according to the prescription, and grind them into coarse powder, add 8 times the weight of water to soak 3- 4 hours, decoct for 1-2 hours, filter and collect the filtrate, add water to the filter residue to 4 times the weight of the medicinal material, decoct for 1-1.5 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.06 (measured at 60°C) ), add ethanol to make the alcohol content reach 43%, let it stand for 12 hours, filter, r...

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Abstract

The invention discloses a pharmaceutical composition for thyroid cancer postoperative recurrent thyroid nodule and a preparation method of the pharmaceutical composition, and belongs to the field of traditional Chinese medicines. The pharmaceutical composition is elaborately prepared from medicinal raw materials including kumquat leaves, jasminum grandiflorum, Chinese fevervine herbs, woolly lespedeza root, holly leaves, urophyllous anotis herbs, false Chinese swertia herbs, calcined concha arcae, moutan barks and dindygulen peperomia herbs. The medicinal raw materials are compatible and have the functions of smoothing the liver, invigorating the spleen, reducing phlegm, resolving masses, activating blood circulation and dissipating blood stasis, clinical symptoms of liver depression and qi stagnation of a patient suffering from the thyroid cancer recurrent thyroid nodule can be effectively relieved, serum TG (triglyceride) level is reduced, the diameter of the thyroid nodule is decreased, and the pharmaceutical composition has a certain preventive and therapeutic effect for cancer recurrence and metastasis and is suitable for clinical application.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for recurrent thyroid nodules after thyroid cancer surgery and a preparation method thereof. Background technique [0002] Thyroid cancer ranks first in both endocrine tumors and head and neck tumors, accounting for about 1% of all solid tumors in the human body. The pathological types are mainly divided into papillary carcinoma, follicular carcinoma, undifferentiated carcinoma, and medullary carcinoma. The main clinical Manifested as neck thyroid lump, pain, hoarseness and difficulty swallowing. In recent years, statistics show that the incidence of thyroid cancer tends to increase, and it has become one of the common malignant tumors. The treatment methods for thyroid cancer include surgery, radiotherapy, chemotherapy, endocrine therapy, etc. Among them, surgery is the first choice for thyroid cancer. However, many studies h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/75A61P35/00A61K35/618
CPCA61K36/75A61K35/618A61K36/185A61K36/48A61K36/51A61K36/63A61K36/65A61K36/67A61K36/71A61K36/74
Inventor 王传秀
Owner QINGDAO YUNTIAN BIOTECH
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