Shangqingyin instant granule and preparation method thereof
A technology of instant granules and supernatant, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, and drug combinations to achieve the effects of good anti-inflammatory health care, easy portability and better taste.
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Embodiment 1
[0042] (1) Take 1 part of myrobalan, 6 parts of frangipani, 7 parts of jelly jelly, 4 parts of fresh reed root, 2 parts of patchouli, and 2 parts of licorice, add 10 times the amount of water to soak for 3 hours, and heat Decoct for 4 hours, decoct for 3 times, combine the decoction liquid, cool to room temperature, and filter;
[0043] (2) Add 95% ethanol to the filtrate obtained in step (1) until the ethanol concentration is 50%, refrigerate, stand overnight, filter, wash the resulting precipitate with ethanol for 3 times, combine the washing liquid with the obtained filtrate, and concentrate under reduced pressure to one-fifth of the original volume to obtain a concentrated solution;
[0044] (3) purifying and refining the concentrated solution obtained in step (2) on a macroporous adsorption resin column, eluting with 0%, 30%, 60%, and 90% ethanol respectively, reclaiming 30% and 60% of the eluted parts, after merging Concentrate under reduced pressure, remove the ethanol...
Embodiment 2
[0048] (1) Take 1 part of myrobalan, 6 parts of frangipani, 7 parts of jelly jelly, 4 parts of fresh reed root, 2 parts of patchouli, and 2 parts of licorice, add 11 times the amount of water to soak for 3.5 hours, Heat and decoct for 3.5 hours, decoct 3 times, combine the decoction liquid, cool to room temperature, and filter;
[0049] (2) Add 95% ethanol to the filtrate obtained in step (1) until the ethanol concentration is 60%, refrigerate, stand overnight, filter, wash the resulting precipitate with ethanol for 3 times, combine the washing liquid with the obtained filtrate, and concentrate under reduced pressure to one-fifth of the original volume to obtain a concentrated solution;
[0050] (3) purifying and refining the concentrated solution obtained in step (2) on a macroporous adsorption resin column, eluting with 0%, 30%, 60%, and 90% ethanol respectively, reclaiming 30% and 60% of the eluted parts, after merging Concentrate under reduced pressure, remove the ethanol...
Embodiment 3
[0054] (1) Take 1 part of myrobalan, 6 parts of frangipani, 7 parts of jelly jelly, 4 parts of fresh reed root, 2 parts of patchouli, and 2 parts of licorice, add 9 times the amount of water to soak for 5 hours, and heat Decoct for 5 hours, decoct for 3 times, combine the decoction liquid, cool to room temperature, and filter;
[0055] (2) Add 95% ethanol to the filtrate obtained in step (1) until the ethanol concentration is 50%, refrigerate, stand overnight, filter, wash the resulting precipitate with ethanol for 3 times, combine the washing liquid with the obtained filtrate, and concentrate under reduced pressure to one-fifth of the original volume to obtain a concentrated solution;
[0056] (3) purifying and refining the concentrated solution obtained in step (2) on a macroporous adsorption resin column, eluting with 0%, 30%, 60%, and 90% ethanol respectively, reclaiming 30% and 60% of the eluted parts, after merging Concentrate under reduced pressure, remove the ethanol ...
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