The invention discloses an oriental cherry milk tea wine and a preparation method thereof. The oriental cherry milk tea wine is prepared from the following raw materials by weight: 15-25 parts of oriental cherry, 10-15 parts of mesona, 30-40 parts of coconut milk, 10-20 parts of spine date seeds, 20-30 parts of red beans, 15-20 parts of peanuts, 10-20 parts of black tea, 300-400 parts of fresh milk, 20-30 parts of honey, 2-3 parts of semen cuscutae, 1-2 parts of forestry greenstar roots, 2-3 parts of haw seed powder, 2-3 parts of pumpkin flowers, 1-2 parts of lycopodium clavatum, 2-3 parts of merremia yunnanensis leaves, 1-2 parts of gynostemma pentaphylla, 22-30 parts of maltitol, and 500-600 parts of white spirit. The oriental cherry milk tea wine of the invention is simple in preparation method, and high in nutrition value, contains no chemical additives, is plentiful in taste, and is a green and delicious health drink; traditional Chinese medicine components of semen cuscutae, gynostemma pentaphylla and the like are added into the formula, which have the effects of improving human body immunity, protecting liver, resisting cancer, and resisting fatigue, can effectively relieve adverse symptoms such as tiredness and fatigue, and are beneficial to human body health.