A composition capable of significantly improving anti-alcoholic and liver-protecting activity, its preparation method and application

Abstract

The invention provides a compound for obviously promoting anti-alcohol and liver-protecting activities, and a preparation method and application thereof. The compound is composed of royal jelly extract, kudzuvine roots and semen hoveniae, wherein 80% ethanol is adopted for performing hot reflux mixing extraction on kudzuvine roots and semen hoveniae, and the total flavonoid content of the acquired extract is more than or equal to 30%; the royal jelly extract is acquired by extracting royal jelly which is used as a raw material, and the content of royal jelly acid is 10-50%; the mixed extract of kudzuvine roots and semen hoveniae and the royal jelly extract are added into a quick-releasing controllable releasing solid dispersing carrier; and a solid dispersing technique is adopted for preparing the compound. An experiment shows that the compound provided by the invention can obviously prolong the sleep incubation period caused by ethyl alcohol and can shorten the sleep time of mice, can obviously reduce the ethanol concentration in rat blood, and can reduce the influences of ethanol on mouse weight and liver GSH, MDA, TG and ADH. The compound has significance in researching and developing anti-alcohol and liver-protecting drugs, healthcare foods, common functional foods and special diet foods.

Description

technical field [0001] The invention relates to a composition which significantly improves the antialcoholic and liver-protecting activity. In particular, it relates to a combination of royal jelly extract, kudzu root and Hovenia dulcis fruit, which is mixed and extracted by 80% ethanol heat reflux, and the extract and royal jelly extract are prepared by solid dispersion technology. Background technique [0002] Drinking a small amount of alcohol can promote blood circulation, dredge collaterals, and dispel cold, while excessive drinking can produce "alcoholism" (being commonly called as drunkenness). Medically, alcoholism is divided into two types: acute alcoholism and chronic alcoholism. Among them, acute alcoholism refers to the clinical symptoms of nausea, vomiting, dizziness, delirium, agitation, coma, incontinence, respiratory depression and even death brought to patients in a short period of time after excessive drinking; chronic alcoholism refers to the clinical sym...

AI Technical Summary

Problems solved by technology

At present, most of the anti-alcoholic products in the market are chemical drugs and Chinese patent medicine preparations. While anti-alcoholic, they will increase the metabolic burden of the liver and kidneys to varying degrees and cause varying degrees of damage.

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