Device for enhancing medicine curative effect by amplitude modulation electric field

An electric field enhancement and drug technology, applied in the field of medical devices, can solve the problems of drug efficacy enhancement, high voltage unsafe, damage to normal tissues, etc., to achieve the effects of enhanced efficacy, improved permeability, and increased permeability

Pending Publication Date: 2017-06-13
CHANGSHA LIXING MEDICAL TECH CO LTD
View PDF8 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a device that uses amplitude-modulated electric field to enhance the curative effect of drugs. One is to overcome the unsafe use of high voltage in pulse therapy, the invasiveness of direct insertion of insulated electrodes into the body, the pH value of the extracellular fluid in the electrode action area, etc. The shortcoming of damaging normal tissues due to drastic changes; the second is to generate an amplitud

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Device for enhancing medicine curative effect by amplitude modulation electric field
  • Device for enhancing medicine curative effect by amplitude modulation electric field
  • Device for enhancing medicine curative effect by amplitude modulation electric field

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0040] Figure 1A Molecular structure diagram of human cell membrane; Figure 1B Molecular structure diagram of bacterial cell membrane; Figure 2A Schematic diagram of the torque on a dipole under a uniform external electric field; Figure 2B Schematic diagram of dipole turning under a uniform external electric field; Figure 3A Schematic diagram of the torque on a dipole under a non-uniform external electric field; Figure 3B Schematic diagram of the turning direction of a dipole under a non-uniform external electric field; Figure 4 Schematic diagram of the structure of the device; Figure 5 Schematic diagram of the circuit operation of the amplitude modulation unit; Figure 6 Schematic diagram of square waveform modulation wave; Figure 7 Carrier diagram of sine wave waveform; Figure 8 Schematic diagram of the amplitude modulation wave shape of square wave modulation; Figure 9 Schematic diagram of the power amplifier unit; Figure 10 Schematic diagram of the outp...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a device for enhancing the medicine curative effect by an amplitude modulation electric field. The device comprises a power supply, a central control unit, a frequency modulation signal generating unit, an amplitude modulation unit, a power amplification unit, an output distribution unit, an insulation electrode and an insulation electrode positioning system, wherein under the control of the central control unit, the frequency modulation signal generating unit generates a required frequency signal; the required frequency signal is modulated by the amplitude modulation unit to generate a square wave form amplitude modulation signal; the square wave from amplitude modulation signal is amplified by the power amplification unit and is then allocated onto one than one pair of insulation electrodes by the output distribution unit, so that an amplitude modulation electric field with the continuous weakness serious sudden change is generated between more than one pair of insulation electrodes. The amplitude modulation electric field with the continuous weakness serious sudden change is applied onto cells; cell membrane generates depolarization and repolarization, so that the membrane permeability reversibility is improved; the quantity of the medicine passing through the cell membranes is increased; the curative effect is enhanced.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and relates to a device for enhancing the curative effect of medicine by using an amplitude-modulated electric field. Background technique [0002] Since 1980, electric fields have been widely used in the fields of biology and medicine, including killing microorganisms, cell fusion, gene transformation and tumor treatment. In 1987, Japanese scholar Okino pioneered electric pulse chemotherapy (EPCT). EPCT is a tumor treatment method that combines electric pulses with electric field strengths as high as kilovolts per centimeter and durations of microseconds or even nanoseconds with chemical drugs. This method only Only a small dose of drugs can kill tumor cells efficiently and with low toxicity, greatly improving the efficacy of chemotherapy drugs and reducing their toxic and side effects. [0003] Electric field therapy can be used in combination with chemotherapy for maintenance therapy ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61M37/00C12N13/00
CPCA61M37/00C12N13/00A61M2205/8206A61M2037/0007
Inventor 谭安德罗立强
Owner CHANGSHA LIXING MEDICAL TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap