Application of Atractylodes macrocephala essential oil in preparation of drugs for treating degenerative arthritis

A bone and joint disease, degenerative technology, applied in the field of application of Atractylodes macrocephala essential oil in the preparation of drugs for the treatment of degenerative bone and joint disease, can solve the problems of easy recurrence, large human body damage, etc., and achieve good curative effect

Inactive Publication Date: 2017-06-27
四川九渊医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Degenerative osteoarthropathy currently has no particularly effective drugs for treatment, mainly through physical therapy to slow down the course of the disease; medication is mainly analgesic

Method used

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  • Application of Atractylodes macrocephala essential oil in preparation of drugs for treating degenerative arthritis
  • Application of Atractylodes macrocephala essential oil in preparation of drugs for treating degenerative arthritis
  • Application of Atractylodes macrocephala essential oil in preparation of drugs for treating degenerative arthritis

Examples

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Effect test

Embodiment 1

[0029] Atractylodes essential oil includes 8.5g atractylone, 3g atractylol and 1.5g atractylactone. The Atractylodes Rhizome essential oil is prepared by the following steps: crush 1Kg Atractylodes Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizome with a particle size of 5mm, then mix it with 1Kg deionized water, and wet 1Kg Atractylodes Rhizome for 13 hours. Continuously pass the water vapor at 150°C slowly through the wet Atractylodes macrocephala, and then condense the mixed steam passing through the wet Atractylodes macrocephala to obtain an oil-water mixture, and use a separatory funnel to separate the oil and water to obtain the essential oil of Atractylodes macrocephala.

Embodiment 2

[0031] Atractylodes essential oil includes 8g atractylone, 2.5g atractylol and 1.5g atractylactone. The Atractylodes Rhizome essential oil is prepared by the following steps: crush 0.9Kg Atractylodes Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizome, particle diameter is 6mm, and then mix with 0.45Kg deionized water, and wet 0.9Kg Atractylodes Rhizoma Rhizome for 7 hours. Slowly pass the water vapor at 170°C through the wet Atractylodes macrocephala, and then condense the mixed steam through the wet Atractylodes macrocephala to obtain an oil-water mixture, and use a separatory funnel to separate the oil and water to obtain the essential oil of Atractylodes macrocephala.

Embodiment 3

[0033] Atractylodes essential oil includes 9g atractylone, 3.5g atractylol and 2.5g atractylide. The Atractylodes Rhizome essential oil is prepared through the following steps: crush 1.1Kg Atractylodes Rhizoma Atractylodes Rhizome with a particle size of 7mm, then mix with 0.33Kg deionized water, and wet the 1.1Kg Atractylodes Rhizome for 20 hours. Continuously pass the water vapor at 200°C slowly through the wet Atractylodes macrocephala, and then condense the mixed steam through the wet Atractylodes macrocephala to obtain an oil-water mixture, and use a separatory funnel to separate the oil and water to obtain the essential oil of Atractylodes macrocephala.

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Abstract

The invention provides novel application of Atractylodes macrocephala essential oil in the field of pharmacy and particularly relates to application of Atractylodes macrocephala essential oil in the preparation of drugs for treating degenerative arthritis. Atractylodes macrocephala essential oil is efficient in improving physiochemical properties of synovial fluid and improving the symptoms of a patient, such as pain and swelling. The Atractylodes macrocephala essential oil is efficient in treating degenerative arthritis, such as slipped disc, foraminal stenosis, meniscal injury, and hyperostosis. The Atractylodes macrocephala essential oil is convenient to prepare and use, is convenient for a patient to use, and has low toxic and side effects.

Description

technical field [0001] The invention relates to the field of pharmacy, in particular to the application of Atractylodes macrocephala essential oil in the preparation of medicines for treating degenerative osteoarthritis. Background technique [0002] Degenerative osteoarthritis, also known as osteoarthritis, degenerative arthritis, senile arthritis, and hypertrophic arthritis, is a degenerative disease caused by aging, obesity, strain, trauma, congenital abnormalities of joints, joint Degeneration of articular cartilage, joint margins and reactive hyperplasia of subchondral bone caused by many factors such as deformity. The disease is more common in middle-aged and elderly people, and it is more likely to occur in weight-bearing joints and joints with more activities (such as cervical spine, lumbar spine, knee joints, hip joints, etc.). Excessive weight bearing or use of these joints can promote degenerative changes. Clinical manifestations include slowly developing joint ...

Claims

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Application Information

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IPC IPC(8): A61K36/284A61P19/02A61P19/08A61P19/04A61P29/00
CPCA61K36/284A61K2236/331
Inventor 曹远东
Owner 四川九渊医药科技有限公司
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