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Preparation method of cold heat-clearing tablet

A cold-clearing and traditional Chinese medicine technology, applied in the field of traditional Chinese medicine, can solve the problems of easy loss of heat-sensitive ingredients, low recovery rate of active ingredients, high extraction temperature, etc., and achieve the effect of more absorption, short concentration time and low concentration temperature

Inactive Publication Date: 2017-08-18
河北唐威药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine uses the decoction method to extract the active ingredients of medicinal materials. In the preparation process of traditional Chinese medicine, there are generally disadvantages such as long extraction time, high extraction temperature, high energy consumption, easy loss of heat-sensitive ingredients, low recovery rate of active ingredients, and troublesome post-processing.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] (1) Weigh 365g Nepeta panicle, 105g mint, 180g Fangfeng, 180g Bupleurum, 105g perilla leaf, 180g kudzu root, 105g bellflower, 140g bitter almond, 105g Angelica dahurica, 365g Kudiding, 290g reed rhizome ;

[0019] (2) Take the Nepeta panicles, mint, and perilla leaves of the above weight, add 8 times the quality water of the above three traditional Chinese medicines, distill and extract the volatile oil for 1.0 hour, and collect the distilled aqueous solution in another container; For the first time, add water with 8 times the quality of the above-mentioned eleven traditional Chinese medicines for the first time, decoct for 1.0 hour, filter to obtain the filtrate; add water with 6 times the quality of the above-mentioned eleven traditional Chinese medicines to the filtered residue, decoct for 1.0 hour, filter to obtain the filtrate; The two filtrates are combined with the distilled aqueous solution;

[0020] (3) The combined decoction was concentrated under reduced pre...

Embodiment 2

[0022] (1) Weigh 375g Nepeta panicle, 113g mint, 188g Fangfeng, 113g Bupleurum, 113g perilla leaf, 188g kudzu root, 113g orange stem, 150g bitter almond, 113g Angelica dahurica, 375g Kudiding and 300g reed rhizome;

[0023] (2) Take the Nepeta panicle, mint, and perilla leaves of the above weight, add 10 times the quality water of the above three traditional Chinese medicines, distill and extract the volatile oil for 2 hours, and collect the distilled aqueous solution in another container; For the first time, add 10 times the quality water of the above-mentioned eleven traditional Chinese medicines for the first time, decoct for 1 hour, filter to obtain the filtrate; add 8 times the quality of the above-mentioned eleven traditional Chinese medicines to the filter residue, decoct for 1 hour, filter to obtain the filtrate; The two filtrates are combined with the distilled aqueous solution;

[0024] (3) Concentrate the combined solution under reduced pressure at 70°C to a relativ...

Embodiment 3

[0026] (1) Weigh 385g Nepeta panicle, 120g mint, 195g Fangfeng, 195g Bupleurum, 120g perilla leaf, 195g kudzu root, 120g bellflower, 160g bitter almond, 120g Angelica dahurica, 385g Kudiding, 310g reed rhizome;

[0027] (2)) Take the above-mentioned weight of Nepeta chinensis, mint, and perilla leaves, add 12 times the quality of the above-mentioned three traditional Chinese medicines, distill and extract the volatile oil for 2 hours, and collect the distilled aqueous solution in another container; add water to decoct the dregs of the medicine and the other eight herbs For the second time, add 12 times the quality water of the above-mentioned eleven traditional Chinese medicines for the first time, decoct for 2.0 hours, filter to obtain the filtrate; add 10 times the quality of the above-mentioned eleven traditional Chinese medicines to the filter residue, decoct for 2 hours, filter to obtain the filtrate ; Twice the filtrate is combined with the distilled aqueous solution;

...

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PUM

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Abstract

The invention discloses a preparation method of a cold heat-clearing tablet. The preparation method comprises the following steps: (1) weighing raw materials; (2) preparing three traditional Chinese medicines of schizonepeta spikes, mint and perilla leaves, adding water which is 8-12 times of mass of weights of the traditional Chinese medicines, distilling to extract volatile oil for 1.0-2.0 hours, and collecting a distilled water solution; adding water into decoction residues and other medicines, and carrying out decoction twice, namely adding water which is 8-12 times of mass of the all traditional Chinese medicines, carrying out decoction for 1.0-2.0 hours, and filtering, so as to obtain a filtrate; adding water which is 6-10 times of mass of the all traditional Chinese medicines into the filtered decoction residues, carrying out decoction for 1.0-2.0 hours, and filtering, so as to obtain a filtrate; combining two filtrates with the distilled solution; and (3) combining decoction solutions, carrying out reduced pressure concentration, adding auxiliary materials, carrying out granulation, spraying the volatile oil obtained in the step (2), and carrying out tabletting, so as to form a base tablet, or a coated film or a sugar coating, namely the cold heat-clearing tablet. The preparation method has the beneficial effects that the extraction temperature is low, the energy consumption is low, the extraction time is short, the loss of temperature-sensitive components is low, and the recovery rate of effective components is high.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a preparation method of Ganmao Qingre Tablet. Background technique [0002] Flu is a common disease affecting the health of patients, which can lead to poor mental state of patients, and has a great impact on life and work. Cold is also a kind of acute infectious rhinitis, commonly known as "cold". It is caused by respiratory viruses, among which coronavirus and rhinovirus are the main pathogenic viruses. The virus is excreted and spread from respiratory secretions. When the body's resistance decreases, such as cold, malnutrition, excessive fatigue, excessive smoking and alcohol, systemic diseases, and chronic diseases of the nose itself that affect the smoothness of the respiratory tract, infections are easily induced. At present, more and more people choose to use traditional Chinese medicine because of the small side effects of traditional Chinese medici...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/20A61K9/28A61P11/00
CPCA61K36/899A61K9/2059A61K9/2806A61K9/2826A61K36/232A61K36/233A61K36/238A61K36/346A61K36/488A61K36/534A61K36/535A61K36/538A61K36/66A61K36/736A61K2236/39A61K2236/51A61K2236/331A61K2300/00
Inventor 李宗悟
Owner 河北唐威药业有限公司
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