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Compound celery seed pagodatree flower bud extract and medical application thereof

A technology of extracting Sophora japonica and celery seed, which is applied in the field of medicine, can solve the problems of large side effects and poor curative effect, and achieve the effect of low toxicity

Active Publication Date: 2017-11-21
BEIJING HUMANWELL JUNWEI PHARM TECH CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Poor curative effect and large side effects have become the bottleneck of its clinical application

Method used

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  • Compound celery seed pagodatree flower bud extract and medical application thereof
  • Compound celery seed pagodatree flower bud extract and medical application thereof
  • Compound celery seed pagodatree flower bud extract and medical application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Take 500 g of celery seed and 500 g of Sophora japonica, add 10 times the weight of 60% (V / V) ethanol and ultrasonically extract 3 times, each time for 45 minutes. The extract was concentrated under reduced pressure and dried in vacuo to obtain Extract 1 of the present invention (30 g).

[0054] The extract 1 prepared above was mixed evenly with equal weight of dextrin, and packed into capsules. Each capsule contained 8 g of extract equivalent to the weight of the total medicinal material (the sum of the weights of celery seed and pagoda japonica).

Embodiment 2

[0056] Take 1000 g of celery seed and 500 g of Sophora japonica, add 8 times the weight of 50% (V / V) ethanol and ultrasonically extract them twice, each time for 30 minutes. The extract was concentrated under reduced pressure and dried in vacuo to obtain the extract 2 of the present invention (26 g).

[0057] The above-prepared extract 2 was evenly mixed with equal weight of starch, and packed into capsules. Each capsule contained a composition equivalent to 6 g of the total medicinal material weight (the sum of the weights of celery seed and pagoda japonica).

Embodiment 3

[0059] Take 2000 g of celery seed and 500 g of Sophora japonica, add 10 times the weight of 70% (V / V) ethanol for ultrasonic extraction 4 times, each time for 60 minutes. The extract was concentrated under reduced pressure and dried in vacuo to obtain Extract 3 (44 g) of the present invention.

[0060] The above-prepared extract 3 was evenly mixed with an equal weight of dextrin, and packed into capsules. Each capsule contained a composition equivalent to 5 g of the total weight of the medicinal materials (the sum of the weights of celery seed and pagoda japonica).

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Abstract

The invention relates to a compound celery seed pagodatree flower bud extract and medical application thereof. The compound celery seed pagodatree flower bud extract is obtained in the mode that celery seeds and pagodatree flower buds are extracted in an alcohol solvent. The extract has the reliable uric acid lowering effect, gout caused by hyperuricemia can be effectively prevented or treated, and the extract is low in toxicity and can be made into various preparations for oral long-term maintenance medication use.

Description

technical field [0001] The invention belongs to the field of medicine and relates to a compound celery seed Sophora japonica extract which can be used for treating hyperuricemia and gout. Background technique [0002] Celery seed is the seed of Umbelliferae celery (Apium graveolens L.). Celery, also known as parsley and dry celery, is recorded in "Luxianyan Materia Medica". It is an annual or biennial herb of Umbelliferae, and it is cultivated all over the country and around the world. Celery seed is often used in condiments and foods. Celery seed tea has a significant effect on promoting sleep. Its extract has a contraction effect on pregnant and non-pregnant uteri and can be used to treat dysmenorrhea. Traditional Chinese medicine believes that celery seed has the effects of dispersing qi, reducing swelling, diuresis, opening blockage, and lowering blood pressure. and nephropathy diuretics are used clinically. It has been reported in domestic and foreign literature that...

Claims

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Application Information

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IPC IPC(8): A61K36/489A61P19/06
CPCA61K36/23A61K36/489A61K2236/333A61K2300/00A61P19/06A61P9/12A61K2236/37
Inventor 高永良卢兗伟孙建宁陈海生赵京
Owner BEIJING HUMANWELL JUNWEI PHARM TECH CO LTD
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