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Seasnake compound preparation

A compound preparation, sea snake technology, applied in anti-inflammatory agents, pharmaceutical formulas, non-central analgesics, etc., to achieve good patient compliance, increase drug selection, and overcome the inconvenience of clinical use

Inactive Publication Date: 2017-12-08
HAINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The sea snake compound preparation of the present invention and its use have not yet been reported in the literature and disclosed in patents

Method used

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Examples

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Effect test

Embodiment Construction

[0022] Example 1: The sea snake compound preparation of the present invention can be prepared by the following process steps: 1. Extract the sea snake compound (sea snake: angelica: tempeh ginger = 4:1:3) extract from 75% ethanol (relative density 1.2-1.3, 60°C), add 0.8 times the dry paste amount of auxiliary materials (microcrystalline cellulose: starch = 1:1), fully stir and mix, and dry; 2. Crush the dried material in step 1, and then use 85% ethanol to prepare Soft material, 20 mesh granulation, drying; 3. The dried granules in step 2 are granulated in 16 mesh under the environment where the relative humidity does not exceed 35%, and the fine powder is removed by 60 mesh, and filled with No. 1 capsule to obtain the sea snake compound preparation .

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Abstract

The invention discloses a seasnake Chinese herbal medicine compound preparation achieving the effect of treating rheumatism. 4 parts of seasnakes, 1 part of angelica sinensis and 3 parts of litsea cubeba are extracted by adding ethyl alcohol with the concentration being 75%, adjuvant material pellets which are 0.8 time of a dry extract amount are added, a capsule is filled, and the seasnake Chinese herbal medicine compound preparation is prepared. A complete freund adjuvant (CFA) rat arthritis model research shows that the preparation has a good preventive and therapeutic effect on a rat adjuvant arthritis primary symptom and a secondary symptom, and the good prospect of the seasnake Chinese herbal medicine compound preparation on the aspect of treating rheumatic diseases is displayed. According to the seasnake Chinese herbal medicine compound preparation, compared with original injection, the safety of medicine is enhanced, and the drug selection of patients and the compliance are increased.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation, in particular to a sea snake traditional Chinese medicine compound preparation with rheumatism treatment effect, which belongs to the field of traditional Chinese medicine. Background technique [0002] Sea snake is warm and salty in nature, has the effects of expelling wind and dampness, relaxing tendons and activating collaterals, and is included in the standards of Chinese medicinal materials in Guangxi and Guangdong. Sea snakes are mainly distributed in my country's Hainan, Guangxi and other provinces, and are characteristic and advantageous marine resources in the South my country Sea and the Beibu Gulf. Sea snake folks often use it to make soup to nourish and strengthen, and to soak in wine to treat wind-cold-damp arthralgia. Modern pharmacological studies have shown that sea snake ethanol extract has a good inhibitory effect on rheumatic diseases. Angelica sinensis is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61K9/48A61P19/02A61P29/00A61K35/583
CPCA61K9/1652A61K35/583A61K36/232A61K36/54A61K2300/00
Inventor 赵李妮龚敏梁振纲蒋璐杨先会邓世明
Owner HAINAN UNIVERSITY
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