Medicament integrating traditional Chinese and western medicines for treating acute heart failure and preparation method

An acute heart failure and pharmaceutical technology, applied in the field of medicine, can solve the problems of shortened ventricular diastolic period, increased pulmonary venous pressure, left atrial blood stasis expansion, etc. Effect

Inactive Publication Date: 2018-04-17
刘庆东
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 2. Mitral valve stenosis, especially when accompanied by tachycardia, the diastolic period of the ventricle is shortened, the blood of the left atrium cannot fully flow into the left ventricle, and the blood stasis of the left atrium expands, thus causing an increase in pulmonary venous pressure
[0007] 4. If the infusion is too fast or too much, the load on the heart suddenly increases, which can cause acute pulmonary venous hypertension in patients with original left heart failure

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] The weight number of the raw material composition of described Chinese medicinal composition is Lei Gonglian 42g, Mao Dongqing 42g, Jin Jingshi 35g, horseradish grass 36g, Ophiopogon japonicus 35g, Gengtongcao 27g, Acacia vine 25g, medlar 35g, Xiangqing 33g, 40g Mufangji, 40g Rehmannia glutinosa, 32g Serpentine vine fruit and 23g small red garlic root; the western medicine ingredients include 4g medigoxin, 5g deacetyllanatoside, 2g bumetanide, 3g betamethasone and vitamin B 1 4g.

[0054] A preparation method for a medicament for treating acute heart failure with integrated traditional Chinese and western medicine, comprising the following process steps:

[0055] (1) Lei Gonglian, Mao Dongqing, horseradish grass, Ophiopogon japonicus, Gengtongcao, Acacia vine, Lycium barbarum, Xiangqing, Mufangji, Nansheteng fruit, and small red garlic root are washed and added 6-8 times After heating and decocting a certain amount of distilled water for 2-3 hours, extract it as medici...

Embodiment 2

[0062] The weight number of the raw material composition of described Chinese medicine composition is Lei Gonglian 47g, Mao Dongqing 47g, Jin Jingshi 40g, horseradish grass 39g, Ophiopogon japonicus 38g, Gengtongcao 30g, Acacia 32g, Lycium barbarum 40g, Xiangqing 36g, 44g of Mufangji, 47g of Rehmannia glutinosa, 35g of Serpentine vine fruit and 28g of red garlic root; the western medicine ingredients include 68g of medigoxin, 6g of deacetyllanatoside, 3g of bumetanide, 4g of betamethasone and vitamin B 1 5g.

[0063] The process steps, usage and dosage of the preparation method of the medicament in this embodiment are the same as those in Embodiment 1.

Embodiment 3

[0065] The weight number of the raw material composition of described Chinese medicinal composition is Lei Gonglian 52g, Mao Dongqing 52g, Jin Jingshi 45g, horseradish 42g, Ophiopogon japonicus 42g, Geng Tongcao 33g, Acacia 39g, Lycium barbarum 45g, Xiangqing 40g, 49g of Qufangji, 54g of Rehmannia glutinosa, 38g of S. chinensis fruit and 34g of red garlic root; the western medicine ingredients include 7g of medigoxin, 6.5g of deacetylated hair flower, 4g of bumetanide, 4.5g of betamethasone and vitamin B 1 5.5g.

[0066] The process steps, usage and dosage of the preparation method of the medicament in this embodiment are the same as those in Embodiment 1.

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Abstract

The invention relates to a medicament for treating acute heart failure with integrated traditional Chinese and western medicine and a preparation method thereof. The raw materials for making the active ingredients of the medicament include traditional Chinese medicine ingredients, western medicine ingredients and related pharmaceutical excipients. Jingshi, horseradish grass, Ophiopogon japonicus, Gengtongcao, Acacia vine, Lycium barbarum, Xiangqing, Mu Fangji, Rehmannia glutinosa, S. chinensis fruit and small red garlic root; the western medicine ingredients include medigoxin, deacetylated lanatoside, bumetanide, betamethasone and vitamin B1; the medicine of the present invention selects Chinese herbal medicines with the functions of invigorating the liver and kidney, strengthening the heart and calming the qi, calming and treating stranguria, etc., and is equipped with western medicine components with corresponding functions. Compatible use, after taking the drug, the peripheral blood vessels will be expanded, the blood returning to the heart will be reduced, and symptoms such as dyspnea, irritability, and shortness of breath will be relieved. It has a significant effect on the treatment of acute heart failure and its complications.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a medicament for treating acute heart failure with integrated traditional Chinese and western medicine and a preparation method thereof. Background technique [0002] Acute heart failure refers to the decline of myocardial contractility due to the development of organic heart disease, so that the heart cannot discharge all the blood returned to the heart, and the cardiac output is reduced, causing stagnant blood in the pulmonary veins and severe blood supply insufficiency in the arterial system. It is common in acute myocarditis, Myocardial infarction, severe valvular stenosis, acute cardiac volume overload, rapid ectopic rhythm. Clinically, it is characterized by extreme irritability, extreme shortness of breath, coughing up white foam or pink foam sputum, and dry and wet rales in both lungs. [0003] Causes of acute heart failure include: [0004] 1. In extensive acute myoca...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61K9/20A61P9/04A61K31/196A61K31/51A61K31/573A61K31/7048A61K33/00
CPCA61K36/888A61K9/2059A61K31/196A61K31/51A61K31/573A61K31/7048A61K33/00A61K36/185A61K36/28A61K36/37A61K36/48A61K36/59A61K36/804A61K36/815A61K36/83A61K36/88A61K36/8968A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 刘庆东关祥芝
Owner 刘庆东
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