Transdermal patch capable of relieving nasal obstruction

A technology for transdermal patches and nasal congestion, which is applied in the field of external patches, which can solve the problems of low stickiness, easy to fall off, and unsuitable application time of external patches, and achieve the effect of strong stickiness, not easy to fall off, and long-lasting effect

Inactive Publication Date: 2018-06-12
HENAN LINGRUI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In view of the above situation, in order to solve the defects of the prior art, the object of the present invention is to provide a transdermal patch for alleviating nasal congestion, wh

Method used

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  • Transdermal patch capable of relieving nasal obstruction

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Effect test

Embodiment 1

[0009] When the present invention is implemented, it can be made of the following percentages by weight: eucalyptus oil 5%, menthol 2%, acrylate glue 73% and ethanol 20%, and eucalyptus oil, menthol, and ethanol are mixed together and stirred evenly , to get the eucalyptus oil mixture, then add the eucalyptus oil mixture into the acrylate glue, stir to get the intermediate product glue; fix the release layer and the backing layer on the coating machine, and adjust the coating thickness to 150 μm, and put the middle The product glue is coated on the anti-adhesive layer, and then covered with the backing layer, and the paste content is controlled at 140mg / 9.8cm 2 Within the range of paste, the paste roll is obtained after the coating is completed, and the paste roll is die-cut to get it.

Embodiment 2

[0011] When the present invention is implemented, it can also be made of the following percentages by weight: eucalyptus oil 4.5%, menthol 2.5%, acrylate glue 74% and ethanol 19%, and eucalyptus oil, menthol, and ethanol are mixed together and stirred Uniformly, get the eucalyptus oil mixture, then add the eucalyptus oil mixture into the acrylate glue, stir to get the intermediate product glue; fix the anti-adhesive layer and the backing layer on the coating machine, and adjust the coating thickness to 100 μm, put The intermediate product glue is coated on the anti-adhesive layer, and then covered with the backing layer, and the paste content is controlled at 120mg / 9.8cm 2 Within the range of paste, the paste roll is obtained after the coating is completed, and the paste roll is die-cut to get it.

Embodiment 3

[0013] When the present invention is implemented, it can also be made of the following percentages by weight: eucalyptus oil 6%, menthol 1.5%, acrylate glue 72% and ethanol 20.5%, and eucalyptus oil, menthol, and ethanol are mixed together and stirred Uniformly, get the eucalyptus oil mixture, then add the eucalyptus oil mixture into the acrylate glue, stir to get the intermediate product glue; fix the anti-adhesive layer and the backing layer on the coating machine, and adjust the coating thickness to 200 μm, put The intermediate product glue is coated on the anti-adhesive layer, and then covered with the backing layer, and the paste content is controlled at 160mg / 9.8cm 2 Within the range of paste, the paste roll is obtained after the coating is completed, and the paste roll is die-cut to get it.

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PUM

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Abstract

The invention relates to a transdermal patch capable of relieving nasal obstruction and aims to effectively solve the problems that U-shaped inhalants cause discomfort in use and externally-applied patches are short in acting time, excessively low in adhesion and easy to fall off. The technical scheme adopted by the invention is as follows: the transdermal patch capable of relieving nasal obstruction is composed of an anti-adhesion layer 1, an adhesion layer 2 and a backing layer 3, wherein the adhesion layer 2 is an externally-applied product prepared by taking menthol, eucalyptus oil and ethanol as raw materials, taking an acrylate adhesive as a substrate, mixing, coating and die cutting; the adhesion layer is prepared from the following raw materials in percentage by weight: 4-6% of eucalyptus oil, 1.5-2.5% of menthol, 70-76% of acrylate adhesive and 18-22% of ethanol. The transdermal patch is safe and non-toxic and is pleasant in fragrance, convenient to use and free of discomfort;the acrylate adhesive layer is high in viscidity, steady to stick, difficult to fall off and long in acting time, is capable of rapidly relieving the nasal obstruction symptom, and is a great innovation in nasal patch products.

Description

technical field [0001] The invention relates to an external patch, in particular to a transdermal patch for relieving nasal congestion. Background technique [0002] At present, there are inhalants and external patches on the market for external use of nasal congestion caused by rhinitis or colds. Inhalants can improve nasal congestion by placing active ingredients in U-shaped suction tubes. The disadvantage is that there are foreign objects in the nostrils that cause discomfort; The agent is to paste the product on the clothes on the chest or paste the new polymer water-based gel type on the skin surface. The product pasted on the clothes on the chest has a slow onset and short duration, and the polymer water-based gel type product is not sticky. Strong, short duration of action. Therefore, the improvement and innovation on the external use products that cause nasal congestion caused by rhinitis or cold is an urgent problem to be solved at present. Contents of the invent...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61K9/70A61K47/32A61P11/02A61K31/045
CPCA61K9/7053A61K31/045A61K36/61A61K2300/00
Inventor 熊维政熊伟夏辉周琼许娜丽张新枝刘家春李明
Owner HENAN LINGRUI PHARMA
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