Wearable high blood pressure real-time diagnosis and treatment integrated system with controllable drug release
A wearable, high blood pressure technology, which is applied in the fields of drug equipment, diagnosis, medical science, etc., can solve the problems of inaccurate drug dosage, adjustment of dosage, poor detection accuracy, etc., and achieve real-time and accurate blood pressure monitoring, realize blood pressure, Achieving a controlled release effect
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Embodiment 1
[0083] Hypertensive patient A, male, 40 years old, the blood pressure measured in the clinic was 150mmHg systolic and 95mmHg diastolic, and was diagnosed as mild (grade 1) hypertension. The antihypertensive drug is captopril, and the transdermal dosage is 50mg / day. The single-chip microneedle contains 100mg captopril, which meets the dosage required for 48h continuous blood pressure regulation. The blood pressure monitoring device collects blood pressure every 1 minute, sets the systolic blood pressure to 135mmHg, and diastolic blood pressure to 90mmHg as the threshold value. When the blood pressure exceeds any of these values, an instruction is sent to the drug delivery device to release 5mg of the drug, and the blood pressure is collected every 30s within 5 minutes. value. After 5 minutes, if the drop in systolic blood pressure is greater than or equal to 5mmHg, and the drop in diastolic blood pressure is greater than or equal to 3mmHg, it is judged that blood pressure contr...
Embodiment 2
[0085] Hypertensive patient B, female, 50 years old, the blood pressure measured in the clinic was 170mmHg systolic and 105mmHg diastolic, and was diagnosed as moderate (grade 2) hypertension. The antihypertensive drugs were captopril and nifedipine, and the transdermal dosages were 100mg / day and 30mg / day, respectively. The single-chip microneedles contain 200mg captopril and 60mg nifedipine. The blood pressure monitoring device collects blood pressure every 30s, sets systolic blood pressure 135mmHg, diastolic blood pressure 90mmHg as the threshold, when the blood pressure exceeds any of these values, sends instructions to the drug delivery device to release 10mg of captopril and 3mg of nifedipine, and in 3 The blood pressure value is collected every 20s within 1 minute. After 3 minutes, if the systolic blood pressure drops greater than or equal to 5mmHg, and the diastolic blood pressure drops greater than or equal to 3mmHg, it is judged that the blood pressure regulation is ...
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