A kind of pharmaceutical composition and its preparation method and application
A composition and medicine technology, applied in the field of pharmaceutical compositions and their preparation, can solve the problems of long treatment time, obesity, repeated illness, etc., and achieve the effects of reducing the number of coughs, promoting secretion ability, and inhibiting allergic reactions.
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[0027] Further, the preparation method of the pharmaceutical composition comprises:
[0028] Mix the mixed medicinal materials formed by fennel and spinach and 70-100% ethanol solution according to the ratio of solid to liquid: 1:15-25, and reflux extraction for 2-4 times, each time for 0.5-1.5h, concentrate the obtained extract, dry Dry.
[0029] Preferably, the temperature of the reflux extraction is 60-80°C, or 65-75°C, or 70°C.
[0030] Preferably, the ratio of solid to liquid is 1:17-24, or 1:19-22, or 1:20.
[0031] Preferably, the concentration of the ethanol solution is 80-100%, or 90-100%, or 95%.
[0032] Preferably, extraction is performed 2 to 3 times, 0.8 to 1.2 hours each time; or 3 times, 1 hour each time.
[0033] This embodiment also provides a liquid preparation for treating asthma and allergic rhinitis, which is prepared by mixing the above pharmaceutical composition with sterile water to form a 5-500 g / L medicinal liquid and filtering it.
[0034] Prefe...
Embodiment 1
[0038] This embodiment provides a pharmaceutical composition, which comprises fennel fennel and Oxytropis falciparum at a mass ratio of 1:1.
[0039] The preparation method of this pharmaceutical composition comprises:
[0040] The fennel and Oxytropis falciparum were mixed according to the mass ratio of 1:1, and mixed with 95% ethanol according to the ratio of solid to liquid of 1:20, and refluxed and extracted at 70°C for 3 times, each time for 1h. The supernatant is recovered, concentrated, dried, and pulverized to obtain the obtained product.
Embodiment 2
[0042] The present embodiment provides a pharmaceutical composition, which comprises fennel and Oxytropis falciparum at a mass ratio of 1:5.
[0043] The preparation method of this pharmaceutical composition comprises:
[0044] Mix fennel and Oxytropis falciparum at a mass ratio of 1:5, and with absolute ethanol at a solid-to-liquid ratio of 1:15, and extract twice at 80°C under reflux, each time for 1.5h. The supernatant is recovered, concentrated, dried, and pulverized to obtain the obtained product.
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