Application of nifedipine in medium and severe hypertension treating drugs

A technology for nifedipine and high blood pressure, applied in the field of medical drugs, can solve the problems of the speed, magnitude and duration of blood pressure being difficult to grasp, adverse effects on patients and the like

Pending Publication Date: 2019-03-19
山东众鼎嘉成医药科技有限公司
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  • Description
  • Claims
  • Application Information

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Problems solved by technology

Sublingual administration of nifedipine in the treatment of hypertension is difficult to grasp in terms of speed, magnit...

Method used

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  • Application of nifedipine in medium and severe hypertension treating drugs
  • Application of nifedipine in medium and severe hypertension treating drugs
  • Application of nifedipine in medium and severe hypertension treating drugs

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Embodiment Construction

[0055] The application of nifedipine of the present invention in the treatment of moderate and severe hypertension is described in detail below in conjunction with the accompanying drawings.

[0056] The present invention proposes the application of sublingual administration of nifedipine dripping pills with a small dose of 5 mg in the emergency treatment of moderate and severe hypertension.

[0057] For the application of the nifedipine of the present invention in the medicine for treating moderate and severe hypertension, the dosage of the nifedipine adopts the specification of 5 mg, the dosage form of the nifedipine adopts dropping pills, and oral mucosa is used for administration.

[0058] Oral mucosal administration adopts sublingual administration.

[0059] The frequency of oral mucosal administration adopts:

[0060] Sublingual administration for the first time;

[0061] Or, after the initial sublingual administration, repeat the sublingual administration once at an i...

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Abstract

The invention provides an application of nifedipine in medium and severe hypertension treating drugs and belongs to the technical field of medical drugs. The application is specifically an applicationof sub-lingual administration of 5 mg nifedipine in medium and severe hypertension first aid drugs. The frequency of the oral mucosa administration is as follows: sub-lingual administration initially; or, after sub-lingual administration initially, carrying out sub-lingual administration once every 20 minutes, no more than three times of sub-lingual administration repeatedly are available, that is, the total administration number of times does not exceed 4 times. The preparation from, the administration dosage, the administration path and the administration scheme are provided, and the safetyand effectiveness of sub-lingual administration of small dosage 5 mg nifedipine applied in medium and severe hypertension first aid drugs. The application is a novel breakthrough of the pharmacy modeof nifedipine. The nifedipine dropping pills as preparation transform are primarily used for treating stenocardia and hypertension. The nifedipine dropping pills are quick to take effect by sub-lingual administration, can be stopped anytime, are easily accepted and are also suitable for patients hard to swallow.

Description

technical field [0001] The invention relates to the technical field of medical medicines, in particular to the application of nifedipine in medicines for treating moderate and severe hypertension. Background technique [0002] Hypertension is a common chronic disease and the most important risk factor for cardiovascular and cerebrovascular diseases. Stroke, myocardial infarction, heart failure and chronic kidney disease may all become its main complications. From 115 / 75mmHg to 185 / 115mmHg, every 20mmHg increase in SBP or 10mmHg increase in DBP will double the risk of cardiovascular and cerebrovascular complications. [0003] 30% of the world's people die from cardiovascular diseases such as stroke and heart accident, of which 62% of stroke deaths are directly caused by high blood pressure, and 49% of myocardial infarctions are directly caused by high blood pressure. Reducing the blood pressure level of hypertensive patients is the key to reducing cardiovascular and cerebrov...

Claims

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Application Information

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IPC IPC(8): A61K31/4422A61K9/20A61P9/12
CPCA61K9/006A61K9/2063A61K31/4422A61P9/12
Inventor 张抒扬翟蔚林
Owner 山东众鼎嘉成医药科技有限公司
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