Sterilizing agent capable of inhibiting Klebsiella pneumonia

Abstract

The invention discloses a sterilizing agent capable of remarkably inhibiting growth and propagation of Klebsiella pneumonia. The main component of the sterilizing agent is lipstatin. The sterilizing agent comprises the following components in percentage by mass: 5-13% of lipstatin, 0.5-2% of an ethylenediaminetetraacetic acid (EDTA) disodium salt and 0.5-2% of NaOH. The invention provides the sterilizing agent for inhibiting the growth and propagation of the Klebsiella pneumoniae, can be used for indoor disinfection, particularly can be used for public places such as hospitals and the like where the Klebsiella pneumoniae is spread easily, and has a good effect on inhibiting the growth and propagation of the Klebsiella pneumoniae.

Description

technical field [0001] The invention relates to a sterilizing agent for inhibiting Klebsiella pneumoniae. Background technique [0002] Klebsiella (Klebsiella) is a class of encapsulated Gram-negative bacilli in the Enterobacteriaceae, including Klebsiella pneumoniae (also known as Klebsiella pneumoniae), Klebsiella stinky nose and rhinosclerosis Klebsiella is closely related to humans, especially Klebsiella pneumoniae, which accounts for more than 95% of Klebsiella infections. It is an important pathogen of respiratory tract infection, often causing severe pneumonia, and can also It causes serious diseases such as urinary tract infection, biliary tract infection, sepsis and suppurative meningitis, and is one of the important opportunistic pathogenic bacteria and iatrogenic infection bacteria. [0003] Klebsiella is a relatively short and thick bacillus, with a size of 0.5-0.8×1-2um, arranged alone, in pairs or in short chains. No spores, no flagella, thicker capsule, most...

AI Technical Summary

Problems solved by technology

Nevertheless, the accessible molecular targets on the surface of Klebsiella pneumoniae are very limited given the bulky capsular polysaccharides that shield most surface antigens

On the other hand, easily accessible capsular polysaccharides display a high degree of structural variability and thus antigenic variability, making them unattractive for broad-spectrum antimicrobial approaches