Vaccine adjuvant, application thereof and porcine reproductive and respiratory syndrome vaccine
A respiratory syndrome and vaccine adjuvant technology, which is applied in the field of vaccine adjuvants and porcine reproductive and respiratory syndrome vaccines, can solve the problems of weak cellular immune response and unsatisfactory immune protection effect, so as to reduce viremia and maintain time Longer, less immunosuppressive effects
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0030] A vaccine adjuvant, adding small molecular peptides, diethylaminoethyl glucose and stabilizers to deionized water in sequence, stirring at the maximum speed without foaming, and then adding aluminum hydroxide gel after mixing, the obtained water-soluble Sexual suspension (volume 2mL), the concentration of small molecular peptide in this water-soluble suspension is 1.5mg / mL, the concentration of diethylaminoethylglucose is 1.5g / mL, the concentration of stabilizer is 1g / mL ; The mass fraction of aluminum hydroxide glue accounting for the water-soluble suspension is 10%.
[0031] The pH value of the vaccine adjuvant in this example is 6.8.
[0032] The porcine reproductive and respiratory syndrome vaccine of this embodiment is prepared by mixing the above-mentioned vaccine adjuvant with porcine reproductive and respiratory syndrome virus antigen at a ratio of 1:1.
Embodiment 2
[0034] A vaccine adjuvant, adding small molecular peptides, diethylaminoethyl glucose and stabilizers to deionized water in sequence, stirring at the maximum speed without foaming, and then adding aluminum hydroxide gel after mixing, the obtained water-soluble Sexual suspension (volume is 2mL), the concentration of the small molecular peptide in this water-soluble suspension is 0.5mg / mL, the concentration of diethylaminoethylglucose is 2.5g / mL, the concentration of stabilizer is 0.5g / mL mL; aluminum hydroxide gel accounts for 10% by mass of the water-soluble suspension.
[0035] The pH value of the vaccine adjuvant in this example is 7.8.
[0036] The porcine reproductive and respiratory syndrome vaccine of this embodiment is prepared by mixing the above-mentioned vaccine adjuvant with porcine reproductive and respiratory syndrome virus antigen at a ratio of 1:1.
Embodiment 3
[0038] A vaccine adjuvant, adding small molecular peptides, diethylaminoethyl glucose and stabilizers to deionized water in sequence, stirring at the maximum speed without foaming, and then adding aluminum hydroxide gel after mixing, the obtained water-soluble Sexual suspension (volume is 2mL), the concentration of the small molecular peptide in this water-soluble suspension is 2.5mg / mL, the concentration of diethylaminoethylglucose is 1g / mL, the concentration of stabilizer is 1.5g / mL ; Aluminum hydroxide glue accounts for 20% in mass fractions of the water-soluble suspension.
[0039] The pH value of the vaccine adjuvant in this example is 7.8.
[0040] The porcine reproductive and respiratory syndrome vaccine of this embodiment is prepared by mixing the above-mentioned vaccine adjuvant with porcine reproductive and respiratory syndrome virus antigen at a ratio of 1:1.
PUM
Property | Measurement | Unit |
---|---|---|
concentration | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com