Essence for promoting subcutaneous fat regeneration and preparation process thereof

A technology of subcutaneous fat and essence, applied in skin care preparations, cosmetic preparations, cosmetic preparations, etc., can solve the problems of safety risks, postoperative infection risks, postoperative facial asymmetry, etc., and achieve improved Anti-aging ability, easy to use, good effect

Active Publication Date: 2019-05-31
曾春晨
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problems of safety risk, postoperative infection risk and postoperative facial asymmetry in the existing medical cosmetology through surgical methods, the present invention provides an essence that promotes subcutaneous fat regeneration Liquid, its technical scheme is as follows: a...

Method used

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  • Essence for promoting subcutaneous fat regeneration and preparation process thereof
  • Essence for promoting subcutaneous fat regeneration and preparation process thereof
  • Essence for promoting subcutaneous fat regeneration and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0021] Specific Example 1: First, take 0.05% sodium hyaluronate, 0.5% pyrrolidone carboxylate, 0.05% Sepigel305, 1% glycerin, and 98.38% deionized water into the reaction tank, start stirring, and heat to 75 ~80°C, stir and disperse evenly; then, continue to stir and cool to below 37°C, then take 0.01% SIS3 and 0.01% SB431542 dissolved in 0.01% olive oil, add to the reaction tank and homogenize for 2-3 minutes, Stir to dissolve completely, end.

specific Embodiment 2

[0022] Specific embodiment 2: first take 1.5% sodium hyaluronate, 0.5% pyrrolidone carboxylate, 2.00% Sepigel305, 5% glycerin, and 88% deionized water and add them to the reaction tank, start stirring, and heat to 75 ~80°C, stir and disperse evenly; then, continue to stir and cool to below 37°C, then take 1% SIS3, 1% SB431542 dissolved in 1% olive oil, add to the reaction tank and homogenize for 2-3 minutes, Stir to dissolve completely, end.

specific Embodiment 3

[0023] Specific embodiment 3: first take 0.1% sodium hyaluronate, 0.5% pyrrolidone carboxylate, 2.00% Sepigel305, 5% glycerin, and 92.2% deionized water into the reaction tank, start stirring, and heat to 75 ~80°C, stir and disperse evenly; then, continue to stir and cool to below 37°C, then take 0.1% SIS3 and 0.1% SB431542 dissolved in 1% olive oil, add to the reaction tank and homogenize for 2-3 minutes, Stir to dissolve completely, end.

[0024] The present invention will be further described below in conjunction with the preparation of specific implementation components:

[0025] SIS3 and SB431542 are core effective components for promoting subcutaneous fat regeneration in the present invention, respectively inhibiting signals at different nodes of the TGF beta signaling pathway, and are configured according to different concentrations according to the experimental design. The specific experimental group formulations are as follows:

[0026]

[0027] The performance te...

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Abstract

The invention relates to the technical field of skin anti-aging nursing articles, in particular to an essence for promoting subcutaneous fat regeneration and a preparation process thereof. The essencecomprises the following components in percentage by mass: 0.01-1.00 percent of SIS3, 0.01-1.00 percent of SB431542, 0.05-1.5 percent of sodium hyaluronate, 0.5 percent of pyrrolidone carboxylate acidsalt, 0.01-1 percent of olive oil,1-5 percent of glycerol, 0.05-2.00 percent of Sepigel305 and the balance of deionized water, wherein the sum of components is 100 percent; SIS3 is a novel specific Smad3 inhibitor, which can inhibit phosphorylation suppression TGF-beta and activin signals of Smad3, SB-431542is a transforming growth factor beta receptor (TGF-beta receptor) inhibitor, SIS3 and SB 431542 are all fat-soluble, molecular weights are all less than 800 and can easily penetrate through skin cuticle to enter a basal layer and a dermis layer of skin. The essence is convenient to use, the use effect is good, and the anti-aging ability of skin is greatly improced.

Description

technical field [0001] The invention relates to the field of skin anti-aging care products, in particular to an essence for promoting subcutaneous fat regeneration and a preparation process thereof. Background technique [0002] With the continuous improvement of living standards, people pay more and more attention to health, especially skin care. Skin tissue is the largest tissue and organ of the human body, covering the surface of the human body and blocking the harmful effects of all harmful substances in nature on the living body. However, with the increase of age, the functions of skin tissues and organs are gradually aging. From an aesthetic point of view, it seriously affects people's enthusiasm for life; from a physiological point of view, it affects the effective protection of internal organs of the human body. Skin aging is a comprehensive Generally, as the age continues to grow, subcutaneous fat atrophy, collagen fibers and elastic fiber degeneration continue to ...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/49A61K8/92A61K8/34A61Q19/00
Inventor 杨俊涛史文飚赵凯范信梅
Owner 曾春晨
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