Cosmetic composition containing L-ascorbic acid

A technology of cosmetic composition and ascorbic acid, which is applied in the direction of cosmetics, cosmetic preparations, dressing preparations, etc., can solve the problems of discoloration and inability to better protect L-ascorbic acid, and achieve good long-term stability.

Inactive Publication Date: 2019-08-23
上海宜侬生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, none of the above methods can better protect L-ascor

Method used

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  • Cosmetic composition containing L-ascorbic acid
  • Cosmetic composition containing L-ascorbic acid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-13

[0020] The raw material ratios selected in Examples 1-13 are shown in Table 1. At the same time, Table 1 also shows the pH value and stability data of the cosmetic composition obtained.

[0021] The pH was measured using a Mettler Toledo pH meter.

[0022] The content of L-ascorbic acid was determined using the HPLC method. Chromatographic conditions: Agilent 1200 high performance liquid chromatograph; Chromatographic column: ZORBAX SB-C8 column; Mobile phase: pH2.1 KH 2 PO 4 Solution; Flow rate: 1ml / min; Detection wavelength: 257nm.

[0023] Stability of L-ascorbic acid (%) = 45°C for 1 month or room temperature for one year. L-ascorbic acid concentration / original L-ascorbic acid concentration×100%

[0024] Table 1: The ratio of the raw materials of the cosmetic composition and the stability data

[0025]

[0026]

[0027] It can be seen from Table 1 that the stability of L-ascorbic acid of the cosmetic composition prepared by the formula of the present invention is very good.

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Abstract

The invention provides a cosmetic composition containing L-ascorbic acid. The composition comprises 5-40 wt% of the L-ascorbic acid, 0.2-2 wt% of a cinnamic acid derivative, 5-10 wt% of a glycol etherand/or alkylene glycol solvent, 1.0-50 wt% of polyvinylpyrrolidone and deionized water. By means of the cosmetic composition prepared from the raw materials in the proportion, the L-ascorbic acid ishigh in long-term stability.

Description

Technical field [0001] The invention relates to a stable cosmetic composition containing L-ascorbic acid, belonging to the technical field of cosmetic chemistry. Background technique [0002] L-ascorbic acid, also known as vitamin C, has been widely used in cosmetic formulations due to its safety and effectiveness during topical application. As an effective antioxidant, L-ascorbic acid can remove free radicals in the skin, protect skin cells from damage from the external environment, and prevent photoaging. L-Ascorbic acid can also stimulate collagen synthesis, improve skin elasticity, and reduce fine lines and wrinkles. [0003] However, L-ascorbic acid is very sensitive to temperature and light in the presence of water, resulting in discoloration and decreased content, which has always been a problem for cosmetic formulations. Therefore, there are many ways to try to obtain a stable L-ascorbic acid formulation, including micronization (WO02 / 019972), microencapsulation, and othe...

Claims

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Application Information

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IPC IPC(8): A61K8/34A61K8/67A61K8/81A61Q19/08
CPCA61K8/345A61K8/676A61K8/8176A61Q19/08
Inventor 董长青
Owner 上海宜侬生物科技有限公司
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