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Implantable sensor element and method for detecting at least one analyte in a body fluid

A technology for sensor elements, analytes, applied in the direction of sensors, applications, blood characterization devices, etc., which can solve the problems of limited availability, difficulty, and deterioration of sensor response behavior.

Active Publication Date: 2019-08-27
F HOFFMANN LA ROCHE & CO AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, it is difficult to implement such membranes into sensor designs of known fiber-optic-based sensors without increasing the diffusion process and thus deteriorating the response behavior of the sensor.
Furthermore, the availability of such membranes is limited

Method used

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  • Implantable sensor element and method for detecting at least one analyte in a body fluid
  • Implantable sensor element and method for detecting at least one analyte in a body fluid
  • Implantable sensor element and method for detecting at least one analyte in a body fluid

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Embodiment Construction

[0128] exist figure 1 In, an exemplary embodiment of an implantable sensor element 110 and kit 112 for detecting at least one analyte in a bodily fluid is disclosed. The sensor element 110 may be designed to remain in body tissue for an extended period of time, such as over days or even weeks or months. The sensor element 110 is embodied as a fully implantable transcutaneous sensor element. In general, any type of bodily fluid can be used. Preferably, the bodily fluid is a bodily fluid present in the user's bodily tissue, such as in interstitial tissue. Thus, as an example, the bodily fluid may be selected from the group consisting of blood and interstitial fluid. However, one or more other types of bodily fluids may additionally or alternatively be used. Bodily fluids may generally be contained in bodily tissues. Thus, in general, the detection of at least one analyte in a body fluid can preferably be determined in vivo.

[0129] The sensor element 110 comprises at leas...

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Abstract

An implantable sensor element (110) for detecting at least one analyte in a sample of body fluid is disclosed. The sensor element (110) comprises at least one measurement chamber plate (114) adapted to receive the sample of bodily fluid. The sensor element (110) comprises at least one illumination source (118) designed to generate at least one illumination light beam (120) in at least one spectralrange and to transmit the illumination light beam (120) to the measurement chamber plate (114) such that the illumination light beam (120) at least partially illuminates the measurement chamber plate(114). The measurement chamber plate (114) is designed to generate at least one reflection light beam (130) in response to the illumination by the illumination light beam (120) such that the reflection light beam (130) at least partially illuminates the sample of body fluid within the measurement chamber plate (114). The sensor element (110) comprises at least one optical detector (132) designed to detect at least one property of the reflection light beam (130) and to generate at least one sensor signal dependent on the presence of the analyte. The sensor element (110) furthermore comprises atleast one control unit (126) designed to evaluate the sensor signal.

Description

technical field [0001] The present invention relates to an implantable sensor element and kit for detecting at least one analyte in a bodily fluid and a method for detecting at least one analyte. Devices and methods according to the present invention may primarily be used for long-term monitoring of analyte concentrations in body fluids, such as for long-term monitoring of glucose levels or concentrations of one or more other types of analytes in body fluids. The invention can be applied both in the field of home care and in the field of professional care, such as in hospitals. Other applications are possible. Background technique [0002] Monitoring certain bodily functions, and more particularly monitoring one or more concentrations of at least one metabolite concentration in body fluids, plays an important role in the prevention and treatment of various diseases. Such metabolites may include, by way of example but not exclusively, blood glucose, lactate, cholesterol, or...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/145A61B5/1459
CPCA61B5/686A61B5/14532A61B5/1455A61B5/1459A61B5/14546A61B2560/0214A61B2560/0223
Inventor F.德克H.利斯特W.彼得里克K.哈泽N.克勒格尔-吕
Owner F HOFFMANN LA ROCHE & CO AG
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