Application of mistletoe extract in preparing medicinal product for improving activity of ovarian granular cells

A technology of granulosa cells and extracts, which is applied in the field of preparing traditional Chinese medicine products for improving the activity of ovarian granulosa cells with mistletoe extracts, to achieve the effects of expanding the scope of application, improving the secretion level of estrogen and progesterone, and significantly proliferating

Active Publication Date: 2019-09-27
INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report on the use of mistletoe extract in the preparation of ovary nourishing preparations to improve the activity of ovarian granulosa cells

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1: Preparation of mistletoe water extract

[0015] The dried mistletoe medicinal material is crushed and sieved, soaked in 8 times of water, extracted under heat reflux for 2-4 hours, and the solid dry powder obtained by concentrating the extract under reduced pressure is the alcohol extract of mistletoe.

Embodiment 2

[0016] Example 2: Preparation of mistletoe water extract

[0017] The dried mistletoe medicinal material is crushed and sieved, soaked in 10 times of water, extracted under heat reflux for 2-4 hours, and the solid dry powder obtained by concentrating the extract under reduced pressure is the alcohol extract of mistletoe.

Embodiment 3

[0018] Example 3: Preparation of mistletoe water extract

[0019] The dried mistletoe medicinal material is crushed and sieved, soaked in 12 times of water, extracted under heat reflux for 2-4 hours, and the solid dry powder obtained by concentrating the extract under reduced pressure is the alcohol extract of mistletoe.

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PUM

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Abstract

The invention discloses application of a mistletoe extract in preparing a traditional Chinese medicinal product for improving the activity of ovarian granular cells. According to the invention, novel application of the mistletoe extract in treating ovarian dysfunction and improving the activity of the ovarian granular cells is developed through pharmacological experiments on the basis of preparing the mistletoe extract by fully utilizing traditional Chinese medicinal resources according to the pathogenesis of the ovarian dysfunction and hypotrophy of the ovarian granular cells; and the extract can be added into products of different dosage forms and reaches the activity of nourishing ovary by promoting the proliferation of the ovarian granular cells and improving the estrogen and progesterone secretion levels, is clinically used for treating the ovarian dysfunction, and has the advantages of good curative effects, small side effects, convenience in use and the like.

Description

technical field [0001] The invention belongs to the medical field of traditional Chinese medicine, and in particular relates to a new application of mistletoe extract in preparing traditional Chinese medicine products for improving the activity of ovarian granulosa cells. Background technique [0002] The physiological functions of the ovary include ovulation and endocrine functions, which are of great significance to women's reproductive function, physical and mental health and quality of life. Ovarian dysfunction can lead to ovulation dysfunction, abnormal corpus luteum function and endocrine disorders, etc., which can cause a variety of gynecological diseases, such as uterine dysplasia, infertility, premature ovarian failure, perimenopausal syndrome, etc., and can affect other organs throughout the body. The physiological function of the organ. [0003] The ovary is an important reproductive organ in the reproductive system of female animals. It has two important functio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61K36/815A61K36/232A61K36/638A61K36/39A61K36/43A61P15/08A61K135/00A61K127/00
CPCA61K36/185A61K36/815A61K36/232A61K36/638A61K36/39A61K36/43A61P15/08A61K2236/331A61K2236/51A61K2300/00
Inventor 宋萍萍毛艳韦敏姜晓雁吕晔钱怡云颜露
Owner INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI
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