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Pharmaceutical composition for external use and preparation method thereof

A technology for compositions and external medicines, applied in the directions of drug combinations, pharmaceutical formulations, active ingredients of hydroxyl compounds, etc., can solve the problems of low comprehensive utilization efficiency, single utilization method of puffer fish liver oil, and inability to fully exert biological activity, etc., and achieve good application. Prospect, effect of good treatment effect

Pending Publication Date: 2019-10-25
广州市藻德道科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In view of the above technical problems, the embodiment of the present invention provides a composition for external use and a preparation method thereof, so as to solve the problem that the existing tetrodotoxin or cod liver oil of tetrodotoxin or cod liver oil is relatively single in use, cannot fully exert its biological activity, and has low comprehensive utilization efficiency.

Method used

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  • Pharmaceutical composition for external use and preparation method thereof
  • Pharmaceutical composition for external use and preparation method thereof
  • Pharmaceutical composition for external use and preparation method thereof

Examples

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preparation example Construction

[0050] figure 1 The method flowchart of the preparation method of the compound fugu cod liver oil ointment preparation provided by the embodiment of the present invention. Such as figure 1 Shown, this preparation method comprises the steps:

[0051] 110. Crushing the solid medicine to form medicine powder. The solid medicine includes artificial bezoar, huangling, huanglian, phellodendron, gardenia, dried blood, myrrh, frankincense and licorice.

[0052] Preferably, after the solid drug is pulverized, a sieving operation can be performed to separate the powder with uneven thickness, so as to screen the drug powder with uniform particle size, and the sieve used for the sieving has an aperture of 100 mesh.

[0053] 120. Add an oily substance into the preparation container and raise the temperature to a preset first temperature, so as to melt the oily substance. Such oily substances include petrolatum and lanolin.

[0054] Specifically, the preparation container can be any me...

Embodiment 1

[0065] 1) According to formula 1 shown in the table below, weigh the raw materials to be used.

[0066] 2) Pulverizing the solid traditional Chinese medicine.

[0067] 3) The drug powder obtained after crushing is passed through a 100-mesh sieve before use.

[0068] 4) Put the weighed vaseline and lanolin into a stainless steel batching container with a heating and stirring device, and heat to 80°C until the oily substance is completely dissolved.

[0069] 5) In the case of stirring, add the drug powders of artificial bezoar, scutellaria, coptis, cortex, gardenia, dried blood, myrrh, frankincense, and licorice.

[0070] 6) After adding the drug powder, keep at 80°C and stir for 4 hours.

[0071] 7) After cooling down to 75°C, add puffer fish cod liver oil and continue to stir until it dissolves.

[0072] 8) After continuing to cool down to 30°C, add borneol and vitamin C, and stir evenly at this temperature.

[0073] 9) After the borneol is completely dissolved, filter whi...

Embodiment 2

[0075] 1) 1) According to formula 2 shown in the following table, weigh the raw materials to be used.

[0076] 2) Pulverizing the solid traditional Chinese medicine.

[0077] 3) The drug powder obtained after crushing is passed through a 100-mesh sieve before use.

[0078] 4) Put the weighed vaseline and lanolin into a stainless steel batching container with a heating and stirring device, and heat to 90°C until the oily substance is completely dissolved.

[0079] 5) In the case of stirring, add the drug powders of artificial bezoar, scutellaria, coptis, cortex, gardenia, dried blood, myrrh, frankincense, and licorice.

[0080] 6) After adding the drug powder, keep at 90°C and stir for 4 hours.

[0081] 7) After cooling down to 80°C, add puffer fish cod liver oil and continue to stir until it dissolves.

[0082] 8) After continuing to cool down to 40°C, add borneol and vitamin C, and stir evenly at this temperature.

[0083] 9) After the borneol is completely dissolved, fil...

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Abstract

An embodiment of the invention discloses a pharmaceutical composition for external use and a preparation method thereof. The pharmaceutical composition for external use comprises the following raw materials: puffer fish liver oil, artificial bezoar, radix scutellariae, coptis chinensis, cortex phellodendri, cape jasmine, resina draconis, myrrh, frankincense, liquorice, borneol and vitamin C. According to the pharmaceutical composition for external use, the tetrodotoxin-containing puffer fish liver oil is used as a drug-carrying matrix, and is mixed with monarch drugs, ministerial drugs, adjuvant drugs, conductant drug and the like to prepare the pharmaceutical composition for external use with a composite formula. The pharmaceutical composition for external use has a good treatment effecton various chronic skin diseases, trauma and traumatic infection, and intractable skin diseases which cannot be cured for a long time, and has a good application prospect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine formulas, in particular to a composition for external use and a preparation method thereof. Background technique [0002] With the continuous improvement of social and economic life, various aquatic products or new food varieties have also begun to develop and progress rapidly. On September 5, 2016, the General Office of the Ministry of Agriculture and the State Food and Drug Administration jointly issued the "Notice on Conditionally Liberating the Processing and Operation of Redfin Pufferfish and Pufferfish Obscurus". This allows species of puffer fish such as redfin puffer and obscura puffer to be brought to consumers' tables and eaten as food. [0003] With the opening of the puffer fish market, the artificially cultured puffer fish industry will develop rapidly. The development of these puffer fish industries will greatly increase the visceral waste of puffer fish. How ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K36/896A61K47/06A61P17/00A61K9/06A61K31/045A61K31/375A61K35/413A61K35/60
CPCA61K9/06A61K31/045A61K31/375A61K35/413A61K35/60A61K36/324A61K36/328A61K36/484A61K36/539A61K36/718A61K36/744A61K36/756A61K36/889A61K36/896A61K47/06A61P17/00A61K2300/00
Inventor 黄连生
Owner 广州市藻德道科技有限公司
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