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Traditional Chinese medicine composition for treating liver and kidney deficiency type Parkinson's disease and preparation method thereof

A technology for Parkinson's disease and deficiency of liver and kidney, which can be used in drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients. Difficulty and other problems, to achieve good cardiovascular system effect, improve immunity, no toxic side effects

Inactive Publication Date: 2019-12-24
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Parkinson's syndrome is difficult to cure, and there is no effective treatment method at present. Most of them choose western medicine for treatment. For example, Madopar is currently the "golden drug" for clinical treatment of PD, but most patients will develop symptoms after 5 to 10 years of medication. Different degrees of complications such as drug-induced movement disorders, symptom fluctuations, and psychological disorders, as well as different degrees of adverse drug reactions such as nausea, vomiting, and abdominal pain, cannot prevent the natural development of PD, causing many patients to die due to intolerance. Forced to stop taking the drug

Method used

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  • Traditional Chinese medicine composition for treating liver and kidney deficiency type Parkinson's disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] A traditional Chinese medicine composition for treating liver and kidney deficiency Parkinson's disease, comprising the following Chinese medicinal materials:

[0047] 6 grams of red ginseng, 6 grams of five-finger peach, 6 grams of Maodongqing, 6 grams of Qianjinba, 6 grams of fried Citrus aurantium, 6 grams of broad tendon vine, 6 grams of Sichuan Achyranthes bidentata, 6 grams of cinnamon, and 6 grams of Bupleurum.

[0048] The above-mentioned Chinese medicine composition is prepared into the preparation method of decoction, comprises the following steps:

[0049] Step 1), weigh red ginseng, Wuzhi Maotao, Maodongqing, Qianjinba, fried citrus aurantium, broad tendon vine, Sichuan Achyranthes bidentata, cinnamon, Bupleurum, and mix them evenly to obtain a mixed medicinal material;

[0050] Step 2), add water to the mixed medicinal material obtained in step 1), the weight of the water is 8 times the weight of the mixed medicinal material, soak for 30-60min, decoct with ...

Embodiment 2

[0062] A traditional Chinese medicine composition for treating liver and kidney deficiency Parkinson's disease, comprising the following Chinese medicinal materials:

[0063] 12 grams of red ginseng, 24 grams of five-finger peach, 12 grams of Maodongqing, 36 grams of Qianjinba, 12 grams of fried Citrus aurantii, 18 grams of broad tendon vine, 12 grams of Sichuan Achyranthes bidentata, 12 grams of cinnamon, and 12 grams of Bupleurum.

[0064] The preparation method and usage are the same as in Example 1.

Embodiment 3

[0066] A traditional Chinese medicine composition for treating liver and kidney deficiency Parkinson's disease, comprising the following Chinese medicinal materials:

[0067] 9 grams of red ginseng, 15 grams of five-finger peach, 9 grams of Maodongqing, 21 grams of Qianjinba, 9 grams of fried Citrus aurantium, 12 grams of broad tendon vine, 9 grams of Sichuan Achyranthes bidentata, 9 grams of cinnamon, and 9 grams of Bupleurum.

[0068] The preparation method and usage are the same as in Example 1.

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Abstract

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition with a curative effect and high safety and without toxic and side effects for treating liver and kidney deficiency type Parkinson's disease and a preparation method thereof. The preparation method includes the steps: red ginseng, radix fici simplicissimae, pubescent holly roots, philippine flemingia roots, fried immature bitter oranges, caulis tinosporae sinensis, medicinal cyathula roots, cortex cinnamomi and radix bupleuri are adopted and respectively comminuted with a grinder, sieved, evenly stirred after mixed to obtain mixed medicine powder, and according to a conventional process, granules, capsules, tablets or pills are prepared; or water is added into themedicinal materials, soaking, decocting and filtering are conducted to obtain first-time liquid medicine, water is added into dregs of a decoction, decocting and filtering are conducted to obtain second-time liquid medicine, the first-time liquid medicine and the second-time liquid medicine are combined, filtered, sterilized and sub-packaged to obtain a decoction. The effects of combining deficiency and excess, considering both symptoms and root causes, treating severe and mild symptoms and regulating the interior and exterior are achieved, natural botanical medicines with the effects of tonifying the liver and kidney, calming endogenous wind, reducing phlegm and stopping tremor are screened, and thus the traditional Chinese medicine composition is obtained.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating Parkinson's disease of liver and kidney deficiency type with remarkable curative effect, high safety and no side effects and a preparation method thereof. Background technique [0002] Parkinson's disease, also known as Parkinson's disease, is one of the three major diseases that cause disability in middle-aged and elderly people. It is a common degenerative disease of the nervous system in middle-aged and elderly people. Reflex disorders etc. More common in people over the age of 55, the prevalence rate is about 1%, and increases with age, slightly more men than women. With the proportion of my country's population aging, the incidence of Parkinson's disease continues to increase. [0003] The main pathological features of Parkinson's syndrome are the accumulation of α-synuclein in the brain tissue to form Lew...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P25/16
CPCA61K36/185A61K36/21A61K36/233A61K36/258A61K36/48A61K36/54A61K36/59A61K36/60A61K36/752A61P25/16A61K2300/00
Inventor 沈晓明边颂博苏朝阳王佳彬黄艳丽马云枝贾晓倩左俊岭张杰兰瑞许玉珉
Owner HENAN UNIV OF CHINESE MEDICINE
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