Application of cycloastragenol in preparing medicines for treating or preventing Alzheimer's disease
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- 潘晓东
- Publication Date
- 2020-04-10
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Abstract
Description
technical field
[0001] The invention belongs to the technical field of medicine, and relates to a new medicinal application of cycloastragenol, in particular to the application of cycloastragenol in the preparation of drugs for treating Alzheimer's disease. Cycloastragenol can promote the removal of key pathological amyloid (Aβ) deposits in the brain of Alzheimer's disease, inhibit the inflammatory response of microglial cells, significantly reduce the deposition of aging-related substances in the brain, anti-aging, and improve brain tissue. The ability to metabolize glucose has good protective and therapeutic effects on learning, memory, and behavioral motor ability damage caused by Aβ deposition, so it can be used to prepare drugs for preventing or treating Alzheimer's disease. Background technique
[0002] At present, the core hypothesis of Alzheimer's disease (AD), Aβ, has been developed, and the theory of abnormal immune inflammation has become the mainstream mechanism ...