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Dental material as well as preparation method and application thereof

A dental material and application technology, applied in dental preparations, dentistry, dental prosthesis, etc., can solve the problems of improving the therapeutic activity of dentin tubules and removing pathogenic biofilms

Pending Publication Date: 2020-10-27
SICHUAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

2. The anatomical structure of the root canal system is complex, with complex structures such as accessory root canals, apical divergences, apical furcations, root canal isthmuses, and C-shaped root canals. Traditional root canal preparation is difficult to penetrate into the complex root canal system thoroughly. Removal of pathogenic biofilm, residual bacteria still exist in the narrow part of the root canal and deep in the dentin tubule
However, in clinical use, it has been found that the root canal sealant added with DMADDM has room for improvement in the therapeutic activity of the dentinal tubules

Method used

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  • Dental material as well as preparation method and application thereof
  • Dental material as well as preparation method and application thereof
  • Dental material as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Weigh a certain amount of root canal sealant EndoREZ, add DMADDM with a mass fraction of 2.5%, add magnetic nanoparticles MNP at a mass fraction of 1%, and mix for 5 minutes at room temperature to obtain the dental material of the present invention.

Embodiment 2

[0036] Weigh a certain amount of root canal sealer EndoREZ, add DMADDM with a mass fraction of 2.5%, add ferric iron tetroxide magnetic nanoparticle MNP at a mass fraction of 2%, and carry out mixing treatment at room temperature for 5 minutes to obtain the dental material of the present invention .

Embodiment 3

[0037] Embodiment 3 screening and performance test

[0038] (1) Preparation of experimental materials

[0039] Weigh a certain amount of root canal sealant, add DMADDM with a mass fraction of 2.5%, divide it into 3 groups in equal proportions, add MNP according to the mass fraction of 0%, 1%, and 2%, and carry out mixing treatment at room temperature for 5 minutes. .

[0040] For the EndoREZ group, mix and mix for 5 minutes at room temperature, and set aside.

[0041] (2) Performance testing

[0042] Grouped according to the mass fraction, the cytotoxicity, solubility, sealant penetration to dentin, and antibacterial properties of the above materials were tested respectively, with 6 samples in each group

[0043] A. Cytotoxicity test

[0044] 1. Put the prepared materials of different groups into a cylindrical mold with an inner diameter of 5mm and a height of 2.5mm, and then put the prepared samples in a constant temperature box at 37°C and 100% humidity for 7 days to mak...

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Abstract

The invention provides a dental material. The dental material comprises a resin root canal sealant and DMADDDM, and also comprises magnetic nanoparticles (MNPs). The material can improve the dentin tubule permeability and antibacterial properties of the root canal sealant while maintaining the material properties of the sealant, so that the purpose of preparing a novel resin-type root canal sealant material with effective antibacterial properties and dentin permeability is achieved.

Description

technical field [0001] The invention belongs to the field of dental materials. Background technique [0002] Periodontal pulp and periapical disease is a type of bacterial infectious disease that occurs in the pulp and periapical tissue. After complete and standardized root canal treatment, there is still a failure rate of 10% to 15%, and it may develop into a persistent disease. Periapical periodontitis. There are two main factors that contribute to the failure of root canal treatment. 1. Infection control is not good, and bacterial biofilm in the root canal is not cleared in place. For example, Enterococcus faecalis, a common root canal bacterium, can invade and grow in dentin tubules, and a complex bacterial biofilm can be detected in the periapical site, leading to the destruction of periapical tissues. 2. The anatomical structure of the root canal system is complex, with complex structures such as accessory root canals, apical divergences, apical furcations, root can...

Claims

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Application Information

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IPC IPC(8): A61K6/71A61K6/54A61K6/15A61K6/69A61K6/889
CPCA61K6/71A61K6/54A61K6/15A61K6/69A61K6/889
Inventor 程磊郭笑周学东李继遥张玲李明云
Owner SICHUAN UNIV
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