The invention relates to a compound Chinese medicine for treating multidrug-resistant tuberculosis, which is prepared from following raw medicinal materials: 15 to 20 grams of manyflower solomonseal rhizome, 10 to 20 grams of common bletilla tuber, 15 to 20 grams of heterophylly falsestarwort root, 10 to 15 grams of sessile stemona root, 15 to 20 grams of Japanese ardisia herb, 10 to 15 grams of common coltsfoot flower, 15 to 20 grams of Phippine violet herb, 10 to 12 grams of Japanese thistle herb or root, 15 to 20 grams of cochinchinese asparagus root, and 15 to 20 grams of turtle shell. The compound Chinese medicine capable of treating multidrug-resistant tuberculosis can enhance a curative effect, and has functions of nourishing Yi, moistening lung, killing parasites, eliminating phlegm, removing blood stasis and promoting tissue regeneration. The compound Chinese medicine provided by the invention integrates a western chemotherapy regimen to treat multidrug-resistant tuberculosis, and also can accelerate sputum conversion, promote the absorption of focus, improve immunity, and accelerate the recovery of tuberculosistoxic symptoms.