Method convenient for myocardial metabolism development

A myocardial metabolism and convenient technology, applied in the medical industry, can solve the problems of weak response ability, poor image quality of myocardial metabolism imaging, and unfavorable clinical promotion, so as to improve the level of glucose metabolism, facilitate clinical promotion and application, and improve image quality. Effect

Pending Publication Date: 2020-11-10
THE FIRST PEOPLES HOSPITAL OF CHANGZHOU
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Problems solved by technology

However, diabetics present a unique challenge, either because of their relative inadequacy in producing endogenous insulin or because their cells are less responsive to insulin stimulation, euglycemic-hyperinsulinemic clamp (euglycemic hyperinsulinemic clamp clip) technique is optional, addressing DM patients 18 F-FDG PET myocardial metabolic imaging is the most ideal method with poor image quality, but it is time-consuming and requires high technical skills, which is not conducive to clinical promotion

Method used

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  • Method convenient for myocardial metabolism development
  • Method convenient for myocardial metabolism development
  • Method convenient for myocardial metabolism development

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Experimental program
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Embodiment 1

[0033] Such as figure 1 As shown, a convenient method for myocardial metabolic imaging, specifically includes the following steps:

[0034] S1. Determine the research population. The inclusion criteria are: patients with myocardial infarction or ischemic cardiomyopathy combined with diabetes mellitus; patients with left ventricular ejection fraction <45%; the exclusion criteria are: acute myocardial infarction or unstable angina within 1 month Patients; those with severe arrhythmia; those with normal resting MPI; patients with dilated cardiomyopathy or hypertrophic cardiomyopathy; patients with severe liver, kidney, respiratory system, and blood system diseases. Age, height, weight, smoking status, history of hypertension, history of diabetes, duration of diabetes, treatment methods and blood sugar control, fasting blood sugar and glycosylated hemoglobin, blood lipids, alanine aminotransferase creatinine and troponin levels, NYHA cardiac function class , Coronary angiography ...

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Abstract

The invention discloses a method convenient for myocardial metabolism development. The method comprises the following steps of S1, determining a research population; S2, regulating blood sugar and performing developing; S3, evaluating image quality; S4, performing visual analysis; S5, performing quantitative analysis; S6, performing quantitative analysis on heart function and myocardial viability;and S7, performing counting. According to the method, trimetazidine can increase the glucose metabolism level of normal or ischemic myocardium of a diabetic patient to different extents, remarkably improve the image quality of 18F-FDG myocardial metabolism imaging (MMI), potentially improve the accuracy of gated PET quantitative parameter measurement, is safe and effective, and is combined with an oral glucose load/intravenous injection insulin method for use. Compared with a normal blood sugar hyperinsulinism holder technology, the method disclosed by the invention is more convenient to operate, and clinical application and popularization are facilitated.

Description

technical field [0001] The invention relates to the technical field of the medical industry, in particular to a method for facilitating myocardial metabolic imaging. Background technique [0002] Coronary artery disease (CAD), especially myocardial infarction, remains a leading cause of death and disability in patients with diabetes mellitus (DM), and is more likely to be a complex disease characterized by diffuse and multivessel disease. Coronary revascularization is an important treatment to reduce major adverse cardiac events and mortality, and to relieve angina symptoms. It is generally believed that the qualitative and quantitative evaluation of viable myocardium before coronary revascularization can predict whether postoperative cardiac function and quality of life can be improved, whether left ventricular remodeling can be reversed, and whether the survival rate can be improved, which is helpful to clarify the benefits Hazard ratio, adjuvant therapy strategy developm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00
CPCA61B5/4519A61B5/72A61B2576/023
Inventor 邵晓梁王跃涛张飞飞徐梅
Owner THE FIRST PEOPLES HOSPITAL OF CHANGZHOU
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