Betaine salicylate and preparation method thereof

A technology of salicylate and betaine, which can be used in the preparation of carboxylate, carboxylate, and cyanide reaction, etc., can solve problems such as high irritation, and achieve the effect of reducing irritation.

Pending Publication Date: 2021-02-26
衢州市展宏生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional skin care products and cosmetics added with salicylic acid can play a certain role in

Method used

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  • Betaine salicylate and preparation method thereof
  • Betaine salicylate and preparation method thereof
  • Betaine salicylate and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Take betaine according to the weight ratio: salicylic acid = 50:50, add 100 g of alcohol solvent to dissolve, evaporate part of the solvent to recrystallize, centrifuge and dry to obtain the finished product; the yield reaches 96.5%.

Embodiment 2

[0025] Take betaine according to the weight ratio: salicylic acid = 50:50 mix, add 100g of water solvent to dissolve, evaporate part of the solvent to recrystallize, centrifuge and dry to obtain the finished product; the yield reaches 98%.

Embodiment 3

[0027] Take betaine according to the weight ratio: salicylic acid = 50:50, add to the enamel reaction kettle, gradually heat to 120 ° C, keep the temperature for 2 hours, so that all the solids are melted into liquids, release the solution at high temperature, cool and solidify, and then pulverize; Then add 100 g of alcohol or water solvent to dissolve, evaporate part of the solvent to recrystallize, centrifuge and dry to obtain the finished product; the yield reaches 98%.

[0028] The betaine salicylate prepared by the above method is a novel mild and low-irritation raw material, which can be used in cosmetics and washing products. It can stimulate the vitality of cells, keep the skin moisturized, smooth, and prevent dryness and darkening of the skin. Betaine salicylate can dissolve the cement between the cuticles and make the cuticles fall off, so it can remove accumulation Excessively thick stratum corneum, promotes metabolism.

[0029] The betaine salicylate can remove ex...

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Abstract

The invention provides betaine salicylate and a preparation method thereof, and the preparation method comprises the following steps: mixing betaine and salicylic acid according to a molar ratio or weight ratio of 20-80: 20-80, adding a solvent for dissolving, evaporating to remove part of the solvent for recrystallization, centrifuging, and drying to obtain a finished product. The betaine salicylate provided by the invention is a novel mild low-irritation raw material, and mainly solves the problem of large irritation caused by adding traditional salicylic acid into skin care products and cosmetic formulas; after glycine betaine is connected to a salicylic acid group, the product becomes mild and low in irritation, the effects of sterilization, inflammation diminishing, acne removing andthe like of salicylic acid are kept, and irritation to the skin is effectively reduced.

Description

technical field [0001] The invention relates to a betaine salicylate and a preparation method thereof. Background technique [0002] Salicylic acid is a fat-soluble organic acid, white crystalline powder, which exists in willow bark, white pearl leaves and sweet birch in nature. It is an important fine chemical raw material and can be used in the preparation of aspirin and other drugs. [0003] The main function of the stratum corneum of the skin is to protect the cells of each layer of the skin, and it will naturally flake off under normal circumstances. Old keratin that does not fall off normally will make the skin appear rough and dull, slow down the skin metabolism rate, and even form acne to block pores. Traditional skin care products and cosmetics added with salicylic acid can play a certain role in skin care, but they also have the disadvantage of being highly irritating, which needs to be improved. Contents of the invention [0004] The technical problem to be so...

Claims

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Application Information

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IPC IPC(8): C07C227/18C07C229/12C07C51/41C07C65/10A61K8/44A61K8/365A61Q19/00
CPCC07C227/18C07C229/12C07C51/412C07C65/10A61K8/44A61K8/365A61Q19/00
Inventor 胡新民
Owner 衢州市展宏生物科技有限公司
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